WormBase Tree Display for Gene: WBGene00000112
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| WBGene00000112 | SMap | S_parent | Sequence | Y57G7A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | alh-6 | Person_evidence | WBPerson651 | |||||
| Sequence_name | F56D12.1 | ||||||||
| Molecular_name (13) | |||||||||
| Other_name | xrep-2 | Paper_evidence | WBPaper00051108 | ||||||
| CELE_F56D12.1 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | alh-6 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 16 May 2017 09:45:54 | WBPerson2970 | Name_change | Other_name | xrep-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | alh | ||||||||
| Allele (200) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Contained_in_operon | CEOP2044 | ||||||||
| Ortholog (43) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Concise_description | alh-6 is orthologous to the human gene ALDEHYDE DEHYDROGENASE 4 FAMILY, MEMBER A1 (ALDH4A1; OMIM:606811), which when mutated leads to hyperprolinemia type II. | Curator_confirmed | WBPerson1823 | |||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable 1-pyrroline-5-carboxylate dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to be located in mitochondrial matrix. Expressed in head and tail. Human ortholog(s) of this gene implicated in hyperprolinemia type 2. Is an ortholog of human ALDH4A1 (aldehyde dehydrogenase 4 family member A1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080543 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:406) | ||||
| Molecular_info | Corresponding_CDS | F56D12.1a | |||||||
| F56D12.1b | |||||||||
| F56D12.1c | |||||||||
| F56D12.1d | |||||||||
| Corresponding_transcript | F56D12.1a.1 | ||||||||
| F56D12.1a.2 | |||||||||
| F56D12.1b.1 | |||||||||
| F56D12.1c.1 | |||||||||
| F56D12.1d.1 | |||||||||
| Other_sequence (68) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Chronogram1568 | ||||||||
| Expr6220 | |||||||||
| Expr1014020 | |||||||||
| Expr1030059 | |||||||||
| Expr1152446 | |||||||||
| Expr2009308 | |||||||||
| Expr2027544 | |||||||||
| Drives_construct | WBCnstr00002586 | ||||||||
| Regulate_expr_cluster | WBPaper00059231:alh-6(lax105)_D3Adult_downregulated | ||||||||
| WBPaper00059231:alh-6(lax105)_D3Adult_upregulated | |||||||||
| WBPaper00059231:alh-6(lax105)_L4_downregulated | |||||||||
| WBPaper00059231:alh-6(lax105)_L4_upregulated | |||||||||
| Microarray_results (44) | |||||||||
| Expression_cluster (137) | |||||||||
| Interaction (68) | |||||||||
| Map_info | Map | II | Position | -15.5079 | Error | 0.004302 | |||
| Positive | Positive_clone | F56D12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
