WormBase Tree Display for Gene: WBGene00000112

WBGene00000112 SMap: S_parent: Sequence: Y57G7A
  Identity: Version: 2
    Name: CGC_name: alh-6 Person_evidence: WBPerson651
      Sequence_name: F56D12.1
      Molecular_name (13)
      Other_name: xrep-2 Paper_evidence: WBPaper00051108
        CELE_F56D12.1 Accession_evidence: NDB BX284602
      Public_name: alh-6
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 16 May 2017 09:45:54 WBPerson2970 Name_change: Other_name: xrep-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: alh
    Allele: WBVar00038326
      WBVar01499702
      WBVar02120600
      WBVar00038331
      WBVar00038336
      WBVar01360207
      WBVar00038341
      WBVar00038346
      WBVar00264446
      WBVar00038351
      WBVar00038356
      WBVar00038361
      WBVar00544847
      WBVar00164603
      WBVar00038366
      WBVar00164604
      WBVar00038371
      WBVar00038376
      WBVar01546122
      WBVar01546123
      WBVar00038381
      WBVar01762692
      WBVar01546124
      WBVar01762693
      WBVar01762694
      WBVar00038386
      WBVar01500106
      WBVar00038391
      WBVar00038396
      WBVar02124322
      WBVar00038401
      WBVar02147704
      WBVar02147706
      WBVar01294533
      WBVar01294534
      WBVar00704472
      WBVar00704473
      WBVar00704474
      WBVar00704475
      WBVar00704476
      WBVar00098219
      WBVar00098220
      WBVar00704477
      WBVar00098221
      WBVar00704478
      WBVar00704479
      WBVar00098222
      WBVar00098223
      WBVar00704480
      WBVar02129326
      WBVar00098224
      WBVar00704481
      WBVar00098225
      WBVar00704482
      WBVar00098226
      WBVar00704483
      WBVar00098227
      WBVar00704484
      WBVar00098228
      WBVar00704485
      WBVar00704486
      WBVar00098229
      WBVar00704487
      WBVar00098230
      WBVar00704488
      WBVar00704489
      WBVar00704490
      WBVar00704491
      WBVar00704492
      WBVar00704493
      WBVar00704494
      WBVar00704495
      WBVar00704496
      WBVar00704497
      WBVar00704498
      WBVar00704499
      WBVar00704500
      WBVar00704501
      WBVar01788806
      WBVar00704502
      WBVar00704503
      WBVar01655237
      WBVar01533950
      WBVar01655238
      WBVar01533951
      WBVar01533952
      WBVar01533953
      WBVar01533954
      WBVar01533955
      WBVar01533956
      WBVar01533957
      WBVar01533958
      WBVar01533959
      WBVar01533960
      WBVar01533961
      WBVar01533962
      WBVar01533963
      WBVar01533964
      WBVar00233500
      WBVar01533965
      WBVar01533966
      WBVar01533967
      WBVar01533968
      WBVar01533969
      WBVar01533970
      WBVar02086118
      WBVar02086119
      WBVar01533971
      WBVar02086120
      WBVar01533972
      WBVar01533973
      WBVar01533974
      WBVar01533975
      WBVar01533976
      WBVar01533977
      WBVar01533978
      WBVar01533979
      WBVar01533980
      WBVar01533981
      WBVar01533982
      WBVar01533983
      WBVar02017383
      WBVar01533984
      WBVar01533985
      WBVar02146570
      WBVar01533986
      WBVar02146572
      WBVar01533987
      WBVar02146573
      WBVar00038241
      WBVar01533988
      WBVar01533989
      WBVar01603062
      WBVar01603063
      WBVar00038246
      WBVar00038251
      WBVar00038256
      WBVar00038261
      WBVar00038266
      WBVar00038271
      WBVar00356686
      WBVar00038276
      WBVar00356687
      WBVar00356688
      WBVar00356689
      WBVar00356690
      WBVar00038281
      WBVar00299501
      WBVar00356691
      WBVar01933390
      WBVar00356692
      WBVar01933391
      WBVar01933392
      WBVar00356693
      WBVar00038286
      WBVar01933393
      WBVar00356694
      WBVar01933394
      WBVar00356695
      WBVar01933395
      WBVar00038291
      WBVar00356696
      WBVar00356697
      WBVar02084144
      WBVar00356698
      WBVar00038296
      WBVar00356699
      WBVar02084145
      WBVar02084146
      WBVar02084147
      WBVar00038301
      WBVar01624506
      WBVar02084148
      WBVar01624507
      WBVar02084149
      WBVar02084150
      WBVar01361011
      WBVar01624508
      WBVar02084151
      WBVar01399615
      WBVar01624509
      WBVar00038306
      WBVar01624510
      WBVar01435883
      WBVar01624511
      WBVar02146330
      WBVar01435884
      WBVar00038311
      WBVar01624512
      WBVar02146331
      WBVar01435889
      WBVar01943234
      WBVar02146332
      WBVar00267925
      WBVar00038316
      WBVar00267926
      WBVar01361022
      WBVar00236147
      WBVar00038321
      WBVar00236148
    RNASeq_FPKM (74)
    GO_annotation (14)
    Contained_in_operon: CEOP2044
    Ortholog (43)
    Paralog (11)
    Structured_description: Concise_description: alh-6 is orthologous to the human gene ALDEHYDE DEHYDROGENASE 4 FAMILY, MEMBER A1 (ALDH4A1; OMIM:606811), which when mutated leads to hyperprolinemia type II. Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable 1-pyrroline-5-carboxylate dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to be located in mitochondrial matrix. Expressed in head and tail. Human ortholog(s) of this gene implicated in hyperprolinemia type 2. Is an ortholog of human ALDH4A1 (aldehyde dehydrogenase 4 family member A1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080543 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:406)
  Molecular_info: Corresponding_CDS: F56D12.1a
      F56D12.1b
      F56D12.1c
      F56D12.1d
    Corresponding_transcript: F56D12.1a.1
      F56D12.1a.2
      F56D12.1b.1
      F56D12.1c.1
      F56D12.1d.1
    Other_sequence (68)
    Associated_feature (11)
  Experimental_info: RNAi_result (13)
    Expr_pattern: Chronogram1568
      Expr6220
      Expr1014020
      Expr1030059
      Expr1152446
      Expr2009308
      Expr2027544
    Drives_construct: WBCnstr00002586
    Regulate_expr_cluster: WBPaper00059231:alh-6(lax105)_D3Adult_downregulated
      WBPaper00059231:alh-6(lax105)_D3Adult_upregulated
      WBPaper00059231:alh-6(lax105)_L4_downregulated
      WBPaper00059231:alh-6(lax105)_L4_upregulated
    Microarray_results (44)
    Expression_cluster (137)
    Interaction (68)
  Map_info: Map: II Position: -15.5079 Error: 0.004302
    Positive: Positive_clone: F56D12 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene