WormBase Tree Display for Gene: WBGene00000080
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| WBGene00000080 | Evidence | Paper_evidence | WBPaper00005596 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | T20H4 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | adr-2 | Person_evidence | WBPerson1829 | |||||
| Sequence_name | T20H4.4 | ||||||||
| Molecular_name | T20H4.4 | ||||||||
| T20H4.4.1 | |||||||||
| CE25120 | |||||||||
| Other_name | CELE_T20H4.4 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | adr-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | adr | ||||||||
| Allele (29) | |||||||||
| Strain (16) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (30) | |||||||||
| Contained_in_operon | CEOP3424 | ||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00000079 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00008397 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00011253 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00018857 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00022388 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | adr-2 encodes an adenosine deaminase that acts on RNA (ADAR); ADARs are RNA-editing enzymes that deaminate adenosines to create inosines in double-stranded RNA (dsRNA); adr-2 is expressed ubiquitously in early embryos, as well as in the germline of early adults; ADR-2 is required for ADAR activity in vivo, and for normal chemotaxis. | Paper_evidence | WBPaper00005068 | |||||
| WBPaper00005518 | |||||||||
| WBPaper00005596 | |||||||||
| WBPaper00012788 | |||||||||
| WBPaper00012830 | |||||||||
| WBPaper00012882 | |||||||||
| WBPaper00012897 | |||||||||
| WBPaper00013003 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables double-stranded RNA adenosine deaminase activity. Involved in adenosine to inosine editing; determination of adult lifespan; and positive regulation of chemotaxis. Located in cytoplasm and nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including Aicardi-Goutieres syndrome; Human papillomavirus infectious disease; and dyschromatosis symmetrica hereditaria. Is an ortholog of human ADARB1 (adenosine deaminase RNA specific B1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:225) | ||||
| DOID:0060257 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:225) | ||||||
| DOID:332 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:226) | ||||||
| DOID:0050629 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:225) | ||||||
| DOID:5082 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:225) | ||||||
| DOID:11166 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:225) | ||||||
| DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:225) | ||||||
| Molecular_info | Corresponding_CDS | T20H4.4 | |||||||
| Corresponding_transcript | T20H4.4.1 | ||||||||
| Other_sequence | Oden_isotig11858 | ||||||||
| CBC08338_1 | |||||||||
| Acan_isotig03308 | |||||||||
| Oden_isotig11857 | |||||||||
| CRC08857_1 | |||||||||
| Dviv_isotig23237 | |||||||||
| CR04809 | |||||||||
| Oden_isotig11856 | |||||||||
| Acan_isotig03309 | |||||||||
| Associated_feature | WBsf651187 | ||||||||
| WBsf226939 | |||||||||
| WBsf226940 | |||||||||
| WBsf226941 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00053674 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00113539 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005393 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061890 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00018936 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027767 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8253 | ||||||||
| Expr10878 | |||||||||
| Expr15857 | |||||||||
| Expr1024456 | |||||||||
| Expr1030036 | |||||||||
| Expr1157228 | |||||||||
| Expr2009240 | |||||||||
| Expr2027477 | |||||||||
| Drives_construct | WBCnstr00037747 | ||||||||
| Construct_product | WBCnstr00037747 | ||||||||
| WBCnstr00042566 | |||||||||
| Regulate_expr_cluster (16) | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (108) | |||||||||
| Interaction (40) | |||||||||
| Map_info | Map | III | Position | -0.767922 | Error | 0.000663 | |||
| Positive | Positive_clone | T20H4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4146 | |||||||
| 5431 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (31) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
