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WormBase Tree Display for Gene: WBGene00000079

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Name Class

WBGene00000079EvidencePaper_evidenceWBPaper00005596
SMapS_parentSequenceH15N14
IdentityVersion1
NameCGC_nameadr-1Person_evidenceWBPerson1829
Sequence_nameH15N14.1
Molecular_name (15)
Other_nameadr-1c
adr-1d
adr-1e
adr-1f
adr-1g
CELE_H15N14.1Accession_evidenceNDBBX284601
Public_nameadr-1
DB_infoDatabaseAceViewgene1I353
WormQTLgeneWBGene00000079
WormFluxgeneWBGene00000079
NDBlocus_tagCELE_H15N14.1
PanthergeneCAEEL|WormBase=WBGene00000079|UniProtKB=Q9U3D6
familyPTHR10910
NCBIgene172542
RefSeqproteinNM_182001.5
NM_001392607.1
NM_182003.5
NM_059752.7
NM_059753.8
SwissProtUniProtAccQ9U3D6
TREEFAMTREEFAM_IDTF350325
UniProt_GCRPUniProtAccQ9U3D6
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classadr
Allele (41)
Strain (15)
RNASeq_FPKM (74)
GO_annotation (26)
Ortholog (33)
ParalogWBGene00000080Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008397Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00011253Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00018857Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022388Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionadr-1 encodes, through alternative splicing, at least five isoforms of an adenosine deaminase that acts on RNA (ADAR); ADARs are RNA-editing enzymes that deaminate adenosines to create inosines in double-stranded RNA (dsRNA); adr-1 is expressed in embryos, most or all neurons (e.g., sensory neurons and cilia, the ventral nerve cord, motor neurons and interneurons) and in the developing (but not the adult) vulva; ADR-1 is required for ADAR activity in vivo, and for normal chemotaxis and vulval development; ADR-1 is also required (redundantly with ADR-2) to prevent the silencing of transgenes in somatic tissues by RNAi; ADR-1 (with ADR-2) may protect transgenic RNA from RNAi silencing by deaminating transgenic dsRNA; ADR-1 contains a glutamine/asparagine-rich domain, as well as two N-terminal double-stranded RNA-binding motifs.Paper_evidenceWBPaper00005068
WBPaper00005518
WBPaper00005596
WBPaper00012788
WBPaper00012830
WBPaper00012882
WBPaper00012897
WBPaper00013003
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables mRNA binding activity. Involved in several processes, including adenosine to inosine editing; determination of adult lifespan; and regulation of vulval development. Located in cytosolic ribosome and nucleus. Expressed in body wall musculature; intestine; nervous system; and vulva.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSH15N14.1c
H15N14.1d
H15N14.1e
H15N14.1f
H15N14.1g
Corresponding_CDS_historyH15N14.1a:wp93
H15N14.1b:wp90
H15N14.1b:wp93
Corresponding_transcriptH15N14.1c.1
H15N14.1d.1
H15N14.1e.1
H15N14.1f.1
H15N14.1g.1
Other_sequence (34)
Associated_featureWBsf654806
WBsf656567
WBsf984279
WBsf218070
Experimental_infoRNAi_resultWBRNAi00113526Inferred_automaticallyRNAi_primary
WBRNAi00003276Inferred_automaticallyRNAi_primary
WBRNAi00085502Inferred_automaticallyRNAi_primary
WBRNAi00033718Inferred_automaticallyRNAi_primary
WBRNAi00049411Inferred_automaticallyRNAi_primary
WBRNAi00066848Inferred_automaticallyRNAi_primary
WBRNAi00043426Inferred_automaticallyRNAi_primary
Expr_patternExpr2272
Expr8253
Expr8254
Expr8255
Expr15044
Expr15045
Expr1030035
Expr1153146
Expr2009239
Expr2027476
Drives_constructWBCnstr00010745
WBCnstr00037748
WBCnstr00041884
Construct_productWBCnstr00010745
WBCnstr00037748
WBCnstr00041885
Regulate_expr_cluster (16)
AntibodyWBAntibody00001454
Microarray_results (43)
Expression_cluster (118)
Interaction (92)
Map_infoMapIPosition2.35504Error0.004979
PositivePositive_cloneH15N14Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4145
4160
5503
5665
Pseudo_map_position
Reference (33)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene