WormBase Tree Display for Gene: WBGene00000045
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| WBGene00000045 | Evidence | Person_evidence | WBPerson164 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | ZK973 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | acr-6 | Person_evidence | WBPerson1430 | |||||
| Sequence_name | ZK973.5 | ||||||||
| Molecular_name | ZK973.5 | ||||||||
| ZK973.5.1 | |||||||||
| CE46851 | |||||||||
| Other_name | CELE_ZK973.5 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | acr-6 | ||||||||
| DB_info | Database | AceView | gene | 1E927 | |||||
| WormQTL | gene | WBGene00000045 | |||||||
| WormFlux | gene | WBGene00000045 | |||||||
| NDB | locus_tag | CELE_ZK973.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000045|UniProtKB=Q9N4M3 | |||||||
| family | PTHR18945 | ||||||||
| NCBI | gene | 191479 | |||||||
| RefSeq | protein | NM_058953.3 | |||||||
| TrEMBL | UniProtAcc | Q9N4M3 | |||||||
| UniProt_GCRP | UniProtAcc | Q9N4M3 | |||||||
| OMIM | gene | 118503 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:19 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | acr | ||||||||
| Allele (47) | |||||||||
| Strain | WBStrain00032972 | ||||||||
| WBStrain00035019 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Contained_in_operon | CEOP1922 | ||||||||
| Ortholog (57) | |||||||||
| Paralog (100) | |||||||||
| Structured_description | Concise_description | acr-6 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the UNC-38 subgroup of C. elegans nAChRs; ACR-6 is thus predicted to function in regulation of fast neurotransmission. | Paper_evidence | WBPaper00003425 | |||||
| WBPaper00024530 | |||||||||
| WBPaper00029376 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 20 Jun 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in lung disease (multiple); nicotine dependence; and stomach cancer. Is an ortholog of human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit) and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3905 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1957) | ||||
| DOID:5409 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1957) | ||||||
| DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1957) | ||||||
| DOID:3083 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1957) | ||||||
| DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1957) | ||||||
| DOID:1324 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1957) | ||||||
| DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1957) | ||||||
| DOID:0050742 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1957) | ||||||
| Molecular_info | Corresponding_CDS | ZK973.5 | |||||||
| Corresponding_CDS_history | ZK973.5:wp229 | ||||||||
| Corresponding_transcript | ZK973.5.1 | ||||||||
| Other_sequence | JI172126.1 | ||||||||
| RS09691 | |||||||||
| RSC04005_1 | |||||||||
| Associated_feature | WBsf643212 | ||||||||
| WBsf656202 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00000305 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00004960 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059872 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000757 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1027696 | ||||||||
| Expr1163297 | |||||||||
| Expr1200300 | |||||||||
| Expr2009195 | |||||||||
| Expr2027433 | |||||||||
| Drives_construct | WBCnstr00037772 | ||||||||
| Construct_product | WBCnstr00037772 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (42) | |||||||||
| Interaction | WBInteraction000133959 | ||||||||
| WBInteraction000136792 | |||||||||
| WBInteraction000142025 | |||||||||
| WBInteraction000144319 | |||||||||
| WBInteraction000209430 | |||||||||
| Map_info | Map | I | Position | -1.45686 | Error | 0.017825 | |||
| Positive | Positive_clone | ZK973 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003425 | ||||||||
| WBPaper00005223 | |||||||||
| WBPaper00006324 | |||||||||
| WBPaper00024530 | |||||||||
| WBPaper00024783 | |||||||||
| WBPaper00029012 | |||||||||
| WBPaper00043908 | |||||||||
| WBPaper00046216 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061589 | |||||||||
| Remark | acr-6 was mistakenly connected to ZK973.6 [031022 ck1] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
