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WormBase Tree Display for Gene: WBGene00000041

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Name Class

WBGene00000041SMapS_parentSequenceCHROMOSOME_III
IdentityVersion1
NameCGC_nameaco-2
Sequence_nameF54H12.1
Molecular_nameF54H12.1a
F54H12.1a.1
CE25005
F54H12.1c
CE32436
F54H12.1c.1
F54H12.1c.2
F54H12.1c.3
Other_nameCELE_F54H12.1Accession_evidenceNDBBX284603
Public_nameaco-2
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:19WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classaco
Allele (46)
StrainWBStrain00049342
WBStrain00054746
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (44)
ParalogWBGene00000040Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionaco-2 encodes an aconitase homolog that is required for embryonic viability, fertility, locomotion, and vulval morphogenesis, and perhaps for normal lifespan.Paper_evidenceWBPaper00004424
WBPaper00005655
WBPaper00013184
WBPaper00013598
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable 4 iron, 4 sulfur cluster binding activity and aconitate hydratase activity. Predicted to be involved in tricarboxylic acid cycle. Located in mitochondrion. Expressed widely. Human ortholog(s) of this gene implicated in infantile cerebellar-retinal degeneration and optic atrophy 9. Is an ortholog of human ACO2 (aconitase 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050883Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:118)
DOID:0111442Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:118)
Molecular_infoCorresponding_CDSF54H12.1a
F54H12.1c
Corresponding_CDS_historyF54H12.1b:wp252
Corresponding_transcriptF54H12.1a.1
F54H12.1c.1
F54H12.1c.2
F54H12.1c.3
Other_sequence (145)
Associated_feature (16)
Experimental_infoRNAi_result (15)
Expr_patternExpr4043
Expr1023629
Expr1030021
Expr1152184
Expr2009165
Expr2027402
Drives_constructWBCnstr00037776
Construct_productWBCnstr00037776
Microarray_results (42)
Expression_cluster (179)
Interaction (125)
Map_infoMapIIIPosition-0.455963Error0.00173
PositivePositive_cloneF54H12Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (20)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene