WormBase Tree Display for Disease_model_annotation: WBDOannot00001211
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| WBDOannot00001211 | Disease_term | DOID:0110403 | |
|---|---|---|---|
| Disease_of_species | Homo sapiens | ||
| Modeled_by | Variation | WBVar02153226 | |
| Asserted_gene | WBGene00004187 | ||
| Association_type | is_implicated_in | ||
| Evidence_code | GO_code | IMP | |
| ECO_term | ECO:0007013 | ||
| Modifier_info | Modifier_gene | WBGene00003390 | |
| Modifier_association_type | condition_exacerbated_by | ||
| Genetic_sex | hermaphrodite | ||
| Paper_evidence | WBPaper00059062 | ||
| Disease_model_description | mog-2 (ortholog of human SNRPA1) RNAi exacerbated the phenotypes of prp-8(cer22) animals, indicating that modifier effects of human polymorphisms and other alleles that influence the onset or progression of retinitis pigmentosa can be quickly tested in prp-8 mutant worms. | ||
| Curator_confirmed | WBPerson324 | ||
| Date_last_updated | 26 May 2022 00:00:00 |
