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WormBase Tree Display for Disease_model_annotation: WBDOannot00000430

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Name Class

WBDOannot00000430Disease_termDOID:11723
Disease_of_speciesHomo sapiens
Modeled_byStrainWBStrain00024340
Asserted_geneWBGene00001131
WBGene00001948
Association_typeis_model_of
Evidence_codeGO_codeIMP
ECO_termECO:0007013
Modifier_infoModifier_geneWBGene00000282
Modifier_moleculeWBMol:00004976
Modifier_association_typecondition_ameliorated_by
Genetic_sexhermaphrodite
Paper_evidenceWBPaper00035094
Disease_model_descriptionRNAi-mediated knockdown of cah-4 (carbonic anhydrase) in conjunction with the drug Methazolamide (MTZ) significantly reduced the muscle degeneration in dys-1; hlh-1 double mutants which model Duchenne muscular dystrophy.
Curator_confirmedWBPerson324
Date_last_updated18 May 2017 00:00:00