WormBase Tree Display for Gene: HGNC:9991

HGNC:9991 Identity: Name: CGC_name: Rgs1 Inferred_automatically: AGR_import
      Other_name (12)
      Public_name: Rgs1
    DB_info: Database: HGNC id 9991
        AGR cURI HGNC:9991
        EnsEMBL ENSEMBL_geneID ENSG00000090104
        UniProt UniProt_AC Q08116
    Species: Homo sapiens
    Status: Live
  Gene_info: Biotype: SO:0001217
    Ortholog: WBGene00004351 Caenorhabditis elegans From_analysis: OMA
            OrthoFinder
            Panther
      WBGene00004350 Caenorhabditis elegans From_analysis: OrthoFinder
            Panther
            PhylomeDB
      WBGene00004353 Caenorhabditis elegans From_analysis: OrthoFinder
            Panther
            PhylomeDB
      WBGene00021988 Caenorhabditis elegans From_analysis: OMA
            OrthoFinder
            Panther
    Structured_description: Automated_description: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008] Inferred_automatically: AGR_import