WormBase Tree Display for Gene: HGNC:9376
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HGNC:9376 | Identity | Name | CGC_name | Prkaa1 | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Other_name (17) | ||||||
Public_name | Prkaa1 | |||||
DB_info | Database | HGNC | id | 9376 | ||
AGR | cURI | HGNC:9376 | ||||
EnsEMBL | ENSEMBL_geneID | ENSG00000132356 | ||||
UniProt | UniProt_AC | Q13131 | ||||
DO | id | DOID:3908 | ||||
DOID:12858 | ||||||
DOID:219 | ||||||
DOID:1612 | ||||||
Species | Homo sapiens | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00020142 | Caenorhabditis elegans | From_analysis | Hieranoid | ||
Inparanoid | ||||||
OMA | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |