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WormBase Tree Display for Gene: HGNC:9376

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Name Class

HGNC:9376IdentityNameCGC_namePrkaa1Inferred_automaticallyAGR_import
Other_name (17)
Public_namePrkaa1
DB_infoDatabaseHGNCid9376
AGRcURIHGNC:9376
EnsEMBLENSEMBL_geneIDENSG00000132356
UniProtUniProt_ACQ13131
DOidDOID:3908
DOID:12858
DOID:219
DOID:1612
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00020142Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionThe protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import