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WormBase Tree Display for Gene: HGNC:3596

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Name Class

HGNC:3596IdentityNameCGC_nameFat2Inferred_automaticallyAGR_import
Other_name (15)
Public_nameFat2
DB_infoDatabaseHGNCid3596
AGRcURIHGNC:3596
EnsEMBLENSEMBL_geneIDENSG00000086570
UniProtUniProt_ACQ9NYQ8
OMIMgene604269
DOidDOID:0080287
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00000396Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionThis gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import