WormBase Tree Display for Gene: HGNC:1875
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| HGNC:1875 | Identity | Name | CGC_name | Cfl2 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:1315906 | |||||
| NEM7 | ||||||
| cofilin 2 (muscle) | ||||||
| cofilin, muscle isoform | ||||||
| cofilin-2 | ||||||
| nemaline myopathy type 7 | ||||||
| Public_name | Cfl2 | |||||
| DB_info | Database | HGNC | id | 1875 | ||
| AGR | cURI | HGNC:1875 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000165410 | ||||
| UniProt | UniProt_AC | Q9Y281 | ||||
| OMIM | gene | 601443 | ||||
| DO | id | DOID:0110934 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00006794 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| SonicParanoid | ||||||
| WBGene00302980 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009] | Inferred_automatically | AGR_import |
