WormBase Tree Display for Gene: HGNC:10000
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| HGNC:10000 | Identity | Name | CGC_name | Rgs4 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:70082 | |||||
| DKFZp761F1924 | ||||||
| MGC2124 | ||||||
| MGC60244 | ||||||
| RGP4 | ||||||
| SCZD9 | ||||||
| regulator of G-protein signaling 4 | ||||||
| regulator of G-protein signalling 4 | ||||||
| schizophrenia disorder 9 | ||||||
| Public_name | Rgs4 | |||||
| DB_info | Database | HGNC | id | 10000 | ||
| AGR | cURI | HGNC:10000 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000117152 | ||||
| UniProt | UniProt_AC | P49798 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00004350 | Caenorhabditis elegans | From_analysis | OrthoFinder | ||
| Panther | ||||||
| PhylomeDB | ||||||
| WBGene00004353 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
| Panther | ||||||
| PhylomeDB | ||||||
| Structured_description | Automated_description | Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |
