WormBase Tree Display for GO_term: GO:0007186

GO:0007186 Name: G protein-coupled receptor signaling pathway
  Definition: The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
  Alt_id: GO:0038042
  Synonym: Exact: G protein coupled receptor protein signaling pathway
      G protein coupled receptor protein signalling pathway
      G-protein coupled receptor protein signal transduction
      G-protein coupled receptor protein signaling pathway
      G-protein coupled receptor signalling pathway
      G-protein-coupled receptor protein signalling pathway
      GPCR signaling pathway
      GPCR signalling pathway
    Narrow: dimeric G-protein coupled receptor signaling pathway
      dimeric G-protein coupled receptor signalling pathway
      G-protein coupled receptor signaling pathway via GPCR dimer
  Status: Valid
  Type: Biological_process
  Child: Instance (40)
    Component: GO:0004930
      GO:0099107
  Parent: Instance_of: GO:0007165
  Attributes_of: Motif (271)
    Index: Ancestor: GO:0007154
        GO:0007165
        GO:0009987
        GO:0008150
        GO:0050896
        GO:0051716
        GO:0050789
        GO:0050794
        GO:0065007
        GO:0023052
      Descendant (264)
    GO_annotation (2317)
  Version: Gene Ontology releases/2023-11-15