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WormBase Tree Display for GO_term: GO:0007186

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Name Class

GO:0007186NameG protein-coupled receptor signaling pathway
DefinitionThe series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
Alt_idGO:0038042
Synonym (2)
StatusValid
TypeBiological_process
Child (2)
ParentInstance_ofGO:0007165
Attributes_of (3)
VersionGene Ontology releases/2023-11-15