WormBase Tree Display for Expr_pattern: Expr9949
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| Expr9949 | Expression_of | Gene | WBGene00010621 | ||
|---|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00010621 | ||||
| Expression_data | Life_stage | WBls:0000003 | |||
| WBls:0000041 | |||||
| WBls:0000023 | |||||
| Anatomy_term | WBbt:0003679 | Partial | |||
| Remark | EGG-6::GFP was also observed in some neurons. | ||||
| WBbt:0004540 | Certain | ||||
| WBbt:0005733 | Certain | ||||
| WBbt:0005778 | Certain | ||||
| WBbt:0006748 | Certain | ||||
| WBbt:0008182 | Certain | ||||
| GO_term | GO:0016324 | ||||
| Subcellular_localization | In almost all epithelia where it was expressed, EGG-6::GFP appeared strongly apically enriched. In the excretory duct and pore, EGG-6::GFP lined the luminal membrane. In the epidermis, it was distributed across the apical surfaces of most dorsal and ventral epidermal cells but was observed more weakly or variably in the lateral (seam) epidermis. The fusion was not strongly enriched at apical junctions based on co-visualization with DLG-1/Discs Large::mcherry. The fusion protein partially overlapped with but did not strongly colocalize with transepidermal intermediate filaments at hemidesmosomes. The fusion was present in many large puncta, potentially representing a vesicular compartment trafficking to or from the membrane. | ||||
| Type | Reporter_gene | ||||
| Pattern | EGG-6::GFP was expressed in a subset of epithelial cells, including epidermal, vulval and rectal cells and the excretory duct and pore. EGG-6::GFP was also observed in some neurons. Expression began around the ventral enclosure stage of embryogenesis and continued through larval development, but then decreased in adulthood. Expression was absent from internal epithelia such as the gut and pharyngeal tubes. | ||||
| Reference | WBPaper00040698 | ||||
| Transgene | WBTransgene00010360 |
