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WormBase Tree Display for Expr_pattern: Expr9916

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Name Class

Expr9916Expression_ofGeneWBGene00004270
Reflects_endogenous_expression_ofWBGene00004270
Expression_dataAnatomy_term (13)
GO_termGO:0030425
GO:0005794
GO:0043025
Subcellular_localizationRAB-6.2 is localized to punctate structures in the neuron cell body and along the ventral cord dendrites. We introduced the Pglr-1::cerulean:: rab-6.2 transgene into nematodes that express the Golgi resident protein mannosidase (MANS)::YFP (Rolls et al., 2002; Glodowski et al., 2005) and observed nearly complete colocalization between Cerulean::RAB-6.2 and MANS::YFP, indicating that RAB-6.2 is localized on or near Golgi structures.
TypeReporter_gene
PatternRAB-6.2::GFP is highly expressed in body wall muscles, pharyngeal and vulval muscles, hypodermis, intestine, the gonad, coelomocytes, seam cells, vulval epithelia, distal tip cells, ventral cord dendrites, and neurons. We also introduced this transgene into nematodes that also express a Pglr-1::monomeric RFP (mRFP) transgene (Shim et al., 2004), and we found that RAB-6.2::GFP is expressed in the GLR-1-expressing command interneurons.
PictureWBPicture0000012611
WBPicture0000012612
WBPicture0000012613
ReferenceWBPaper00040563
TransgeneWBTransgene00031307