WormBase Tree Display for Expr_pattern: Expr9225
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| Expr9225 | Expression_of | Gene | WBGene00012990 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00012990 | |||
| Expression_data | Life_stage | WBls:0000024 | ||
| WBls:0000038 | ||||
| WBls:0000027 | ||||
| WBls:0000035 | ||||
| WBls:0000041 | ||||
| WBls:0000015 | ||||
| WBls:0000021 | ||||
| Anatomy_term | WBbt:0004103 | Certain | ||
| WBbt:0004104 | Certain | |||
| WBbt:0005135 | Certain | |||
| WBbt:0006748 | Certain | |||
| WBbt:0006977 | Certain | |||
| GO_term | GO:0005634 | |||
| Subcellular_localization | mCherry-SAM-10 signal became detectable as early as the 1.5-fold stage during embryogenesis. However, SAM-10 is not nuclearly localized at this stage. Using RAB-3-GFP as a marker for PLMs, it was observed that SAM-10 was not nuclearly localized until the late embryonic threefold stage, just before hatching. Thus, SAM-10 translocated into the nucleus in embryonic animals, well before PLM synaptic branches have even formed in early larval stage animals, indicating that SAM-10 nuclear localization is not driven by pre- and postsynaptic cell contact. | |||
| Type | Reporter_gene | |||
| Pattern | The mCherry-SAM- 10 signal was detected broadly throughout the animal with dense expression in the head ganglion,vulva and tail ganglion.sam-10 expression was observed in PLM neurons. Furthermore, using GFP-RAB-3 as a nuclear-excluded marker in the PLM soma, was found that SAM- 10 was nuclearly localized in the PLM. The expression of was characterized using an mCherry-sam- 10 fusion transgene that fully rescues the sam-10(js94) phenotypes. | |||
| Reference | WBPaper00037849 | |||
| Transgene | WBTransgene00030991 |
