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WormBase Tree Display for Expr_pattern: Expr9088

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Name Class

Expr9088Expression_ofGeneWBGene00002981
Reflects_endogenous_expression_ofWBGene00002981
Expression_dataLife_stageWBls:0000024
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
WBls:0000015
WBls:0000021
WBls:0000010
WBls:0000013
Anatomy_termWBbt:0003675Partial
WBbt:0003679Partial
WBbt:0003681Certain
WBbt:0005319Certain
WBbt:0005733Certain
WBbt:0005772Certain
WBbt:0006748Certain
GO_termGO:0005737
GO:0043025
Subcellular_localizationPunctate and diffuse cytoplasmic stainings were observed in early embryos.In larva stages, its expression is mainly diffuse in the cytoplasm but a few dots are often detected in neuron cell bodies and seam cells.
TypeReporter_gene
PatternExpression of GFP::LGG-2 and GFP::LGG-1 is first detected early during embryogenesis (before the 50 cell stage) with both a punctate and a diffuse cytoplasmic staining. At the beginning of organogenesis the number of puncta diminishes and the signal becomes mainly restricted to the pharynx, intestine and hypodermis. After hatching and during larval development GFP::LGG-1 expression has been reported as a diffuse signal predominantly in the lateral hypodermal seam cells and in the pharynx. Similarly, the expression of GFP::LGG-2 is high in the seam cells and pharynx and also in the nervous system, especially in some head and tail neurons and the neuron cell bodies in the ventral nerve cord. Its expression is mainly diffuse in the cytoplasm but a few dots are often detected in neuron cell bodies and seam cells. In adults, the tissue distribution of GFP::LGG-2 and GFP::LGG-1 remains diffuse but becomes more ubiquitous in particular the signal is detected in the whole hypodermis, the muscles, the vulva and the spermatheca. Together these data show that lgg-1 and lgg-2 present widely overlapping expression patterns and suggests the presence of numerous autophagosomal structures during embryogenesis.
RemarkPicture: Fig 2.
ReferenceWBPaper00036347
TransgeneWBTransgene00030898