WormBase Tree Display for Expr_pattern: Expr3924

Expr3924 Expression_of: Gene: WBGene00004800
    Reflects_endogenous_expression_of: WBGene00004800
  Expression_data: Life_stage: WBls:0000024
      WBls:0000003
      WBls:0000038
      WBls:0000027
      WBls:0000035
      WBls:0000041
    Anatomy_term: WBbt:0003679 Certain
      WBbt:0003681 Certain
      WBbt:0005733 Certain
    GO_term: GO:0005634
  Subcellular_localization: SIR-2.1::GFP is primarily localized in the nucleus.
  Type: Reporter_gene
  Pattern: SIR-2.1::GFP is primarily localized in the nucleus and expression is in most if not all neurons in the head and tail from embryo to adult. SIR-2.1::GFP is seen in many pharyngeal cells, where there is no expression of DAF-16::GFP. SIR-2.1::GFP is also expressed in the hypodermis and first seen at the three-fold stage of embryogenesis, diminished by late L3, and low or off in young adults. SIR-2.1::GFP expression was not observed in the intestine and germ line.
  Remark: Several integrated transgenic lines were examined under a fluorescent microscope and showed similar patterns of expression. This SIR-2.1::GFP is functional as it rescues the unc-13(s69); sir-2.1(ok434) strain for life span.
  Reference: WBPaper00026947
  Transgene: WBTransgene00004932