WormBase Tree Display for Expr_pattern: Expr333
expand all nodes | collapse all nodes | view schema
| Expr333 | Expression_of | Gene | WBGene00004267 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004267 | |||
| Expression_data | Anatomy_term | WBbt:0003679 | Certain | |
| Type | Antibody | Antisera against a RAB-3 fusion protein produced in E. coli | ||
| Pattern | ~all neurons. Immunoreactivity was detected in the synaptic-rich regions of the nervous system in a pattern similar to the distribution of the C. elegans synaptic vesicle membrane protein synaptotagmin. Specifically, the nerve ring, ventral nerve cord, and dorsal nerve cord showed the highest immunoreactivity. rab-3 expression also was observed in the pharyngeal nervous system. Detectable levels of RAB-3 were rarely observed in neuronal cell bodies, dendrites of sensory neurons, or the commissural tracts of motor neurons. In contrast to synaptotagmin, RAB-3 protein was not observed at significant levels in the gonadal uv1 neurosecretory cells. Additionally, RAB-3 was not observed in muscle, hypodermis, or intestinal tissue. Analysis of transgenic animals carrying the rab-3::lacZ reporter construct pMG122 confirmed that the gene is expressed in most, if not all, neurons but is not expressed in other tissues. | |||
| Picture | WBPicture0000011060 | |||
| Remark | Data modified according to Shawn Lockery's expression pattern curations. | |||
| Reference | WBPaper00002918 | |||
| Antibody_info | WBAntibody00000151 |
