WormBase Tree Display for Expr_pattern: Expr2889
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| Expr2889 | Expression_of | Gene | WBGene00001332 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00001332 | |||
| Expression_data | Life_stage | WBls:0000041 | ||
| Anatomy_term | WBbt:0003679 | Partial | ||
| WBbt:0005319 | Certain | |||
| GO_term | GO:0005737 | |||
| Subcellular_localization | In neurons, ERI-1 is localized predominantly to the cytoplasm. | |||
| Type | Reporter_gene | |||
| Pattern | In three independent lines, GFP expression was observed in the developing somatic gonad and in a subset of neurons. In adults, ERI-1 was expressed in neurons and gonadal expression was restricted to the spermatheca. The expression and the cytoplasmic localization of the eri-1::GFP fusion was not markedly altered by exposure to dsRNA. | |||
| Remark | Fusion of GFP to the predicted promoter of eri-1 (termed eri-1P::GFP), which was expected to reveal the pattern of expression of both eri-1a and eri-1b, showed a pattern of expression similar to that of eri-1b::GFP. This fusion protein containing only the first five residues of ERI-1 was not localized preferentially to the cytoplasm. Using this construct, low ubiquitous expression was also observed throughout the worm. | |||
| Reference | WBPaper00006382 | |||
| Transgene | WBTransgene00028234 |
