WormBase Tree Display for Expr_pattern: Expr2889
expand all nodes | collapse all nodes | view schema
Expr2889 | Expression_of | Gene | WBGene00001332 |
---|---|---|---|
Reflects_endogenous_expression_of | WBGene00001332 | ||
Expression_data (3) | |||
Subcellular_localization | In neurons, ERI-1 is localized predominantly to the cytoplasm. | ||
Type | Reporter_gene | ||
Pattern | In three independent lines, GFP expression was observed in the developing somatic gonad and in a subset of neurons. In adults, ERI-1 was expressed in neurons and gonadal expression was restricted to the spermatheca. The expression and the cytoplasmic localization of the eri-1::GFP fusion was not markedly altered by exposure to dsRNA. | ||
Remark | Fusion of GFP to the predicted promoter of eri-1 (termed eri-1P::GFP), which was expected to reveal the pattern of expression of both eri-1a and eri-1b, showed a pattern of expression similar to that of eri-1b::GFP. This fusion protein containing only the first five residues of ERI-1 was not localized preferentially to the cytoplasm. Using this construct, low ubiquitous expression was also observed throughout the worm. | ||
Reference | WBPaper00006382 | ||
Transgene | WBTransgene00028234 |