WormBase Tree Display for Expr_pattern: Expr2201
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| Expr2201 | Expression_of | Gene | WBGene00006375 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006375 | |||
| Expression_data | Life_stage | WBls:0000041 | ||
| WBls:0000057 | ||||
| Anatomy_term | WBbt:0005784 | Certain | ||
| GO_term | GO:0005634 | |||
| GO:0000795 | ||||
| Subcellular_localization | SYP-1 protein was observed along the length of synapsed chromosomes during meiotic prophase. Within the premeiotic region of the germ line, SYP-1 protein is not detectable on chromosomes. At or just prior to the beginning of the transition zone, a small number of nuclei are closely associated with one or two SYP-1 foci, while the majority of transition-zone nuclei exhibit several continuous tracks of SYP-1 staining that localize to a portion of the total DAPI-stained chromatin. In the pachytene region, nuclei exhibit highly ordered SYP-1 staining: Thick, continuous lines of SYP-1 lie at the interface between synapsed homologs along their full lengths. Finally, SYP-1 disassembles from the majority of the length of each chromosome pair by diakinesis, and is undetectable on chromosomes by the end of prophase. | |||
| Type | Antibody | Two independent rabbit polyclonal anti-SYP-1 antibodies raised against N-terminal and C-terminal peptides. | ||
| Pattern | Expressed in germ-line cells. | |||
| Picture | WBPicture0000008445 | |||
| WBPicture0000008446 | ||||
| Remark | Antibodies that recognize either the N or C terminus of SYP-1 do not detect SYP-1 protein on chromosomes in germ-line nuclei from syp-1(me17) mutants, further confirming the specificity of the antibody. | |||
| Expression pattern in other life stages or other tissues are not reported in this article. | ||||
| Reference | WBPaper00005462 | |||
| Antibody_info | WBAntibody00000556 | |||
| WBAntibody00000557 |
