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WormBase Tree Display for Expr_pattern: Expr1790

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Name Class

Expr1790Expression_ofGeneWBGene00000905
Reflects_endogenous_expression_ofWBGene00000905
Expression_dataLife_stageWBls:0000024
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
WBls:0000021
WBls:0000032
WBls:0000052
WBls:0000828
WBls:0000829
Anatomy_termWBbt:0004547Certain
WBbt:0004549Certain
WBbt:0004934Certain
WBbt:0004935Certain
WBbt:0005319Certain
WBbt:0005733Certain
WBbt:0005812Certain
WBbt:0005821Certain
WBbt:0006751Certain
GO_termGO:0005783
GO:0048471
Subcellular_localizationDAF-9 was perinuclear, consistent with residence in endoplasmic reticulum.
TypeReporter_gene
Patterndaf-9 was strikingly expressed in a ventral pair of bilateral neurons identified as the IL1Vs or URAVs in the anterior ganglia. Neuronal expression first appeared shortly before hatch, increased greatly during larval development, and perdured in reproductive and postreproductive adults. By mid-L2, DAF-9 also appeared in the cytoplasm of the hypodermis, the syncitial epidermis surrounding the worm, but was absent from midline epidermal seam cells. Levels peaked around the L2 molt and diminished during L4. In some cases, transient expression was seen in L3 vulval blast cells. daf-9 was also expressed within the hermaphrodite spermatheca starting in late L4 larvae, and continuing even in old adults. In some extrachromosomal lines, sporadic weak expression was seen in the excretory cell, a few unidentified head neurons, and vulval muscles. In males, daf-9 was expressed in IL1V/URAVs and hypodermis but not somatic gonad. In dauer larvae, daf-9 was strongly expressed in IL1V/URAV and specifically extended into axonal but not dendritic processes. No hypodermal expression was evident in dauers. In post-dauer stages, daf-9 was expressed in a pattern similar to reproductively growing animals, except expression was absent in the hypodermis.
PictureWBPicture0000009897
ReferenceWBPaper00005054
TransgeneWBTransgene00000399
WBTransgene00000400