WormBase Tree Display for Expr_pattern: Expr16023
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| Expr16023 | Expression_of | Gene | WBGene00006640 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006640 | |||
| Expression_data | Anatomy_term | WBbt:0003681 | Certain | |
| WBbt:0007809 | Certain | |||
| WBbt:0007846 | Certain | |||
| GO_term | GO:0016323 | |||
| GO:0009986 | ||||
| Type | Reporter_gene | |||
| Pattern | We found that TSP-14A and TSP-14B exhibit distinct expression and localization patterns. First, only TSP-14A, but not TSP-14B, is detectable in the germline and sperm cells, as well as at the tip of the anterior sensory cilia, while TSP-14B is detectable in the pharynx. Both TSP-14A and TSP-14B are found in hypodermal cellsand the developing vulva. However, the two isoforms exhibit different subcellular localization patterns. In hypodermal cells, TSP-14A is primarily localized in intracellular vesicles, while TSP-14B is mainly localized on the cell surface. In the developing vulva, TSP-14A is localized on the apical side, while TSP-14B is localized on the basolateral membrane. Similar localization patterns hold true in the pharynx. | |||
| Remark | TSP-14B isoform expression. | |||
| Reference | WBPaper00062426 | |||
| Variation | WBVar02157785 |
