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WormBase Tree Display for Expr_pattern: Expr1584

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Name Class

Expr1584Expression_ofGeneWBGene00000435
Reflects_endogenous_expression_ofWBGene00000435
HomolHomol_homolW03A3:Expr
Expression_dataLife_stageWBls:0000024
WBls:0000004
WBls:0000021
Anatomy_term (13)
TypeReporter_gene
PatternThe large majority of ceh-10 mRNA is found in the embryo and likewise the majority of ceh-10 directed reporter gene expression is also found within the embryo. The earliest point at which ceh-10/lacZ expression can be detected is in a single nucleus at the extreme anterior pole of the embryo, at mid-proliferation stage when the embryo has approximately 350 cells. In late proliferation stage embryos, two nuclei and then four nuclei, all at the embryo anterior, express the transgene. As the embryo begins morphogenesis, six nuclei, all at the very anterior pole, stain for beta-galactosidase activity. By the 1.5-fold stage, the embryo has eight staining nuclei, six at the anterior and two additional cells just ventral to the posterior bulb of the pharynx. By the time the embryo has completed morphogenesis, up to twelve staining nuclei can be detected. ceh-10/lacZ expression in L1 larvae is somewhat variable, in that staining in a particular cell is not always seen in every larva; the likely reason is that the level of ceh-10 mRNA declines after hatching and beta-galactosidase staining in L1 larvae presumably results from enzyme perdurance. Most ceh-10/lacZ staining occurs in the region around the nerve ring, which is dense with the nuclei and processes of neurons. The expressing anterior nuclei were identified as: AIYL/R (interneurons), CEPDL/R (mechanosensory neurons), RID (motor neuron), ALA (lateral neuron), RMED (nerve ring motor neuron), AINL/R (interneurons) and AVJL/R (ventral neurons). ceh-10 is also expressed in the CAN cells (the excretory Canal Associated Neuron).
PictureWBPicture0000007915
ReferenceWBPaper00002186
TransgeneWBTransgene00001684
WBTransgene00001685
WBTransgene00001686