WormBase Tree Display for Expr_pattern: Expr11976
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| Expr11976 | Expression_of | Gene | WBGene00003920 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00003920 | ||
| Type | Reporter_gene | ||
| Pattern | par-5 mRNA isoform selection seemed constant in worms of the same stage but varied considerably during development: total par-5 mRNA abundance decreased during embryogenesis, but the relative amounts of par-5::utr.1 and par-5::utr.2 increased significantly, peaking at the first larval stage. During postembryonic development, par-5 mRNA isoform selection shifted progressively toward the short 3' UTR isoform, par-5::utr.3, in line with the general tendency for C. elegans 3' UTRs (Mangone et al., 2010). This elaborates the results of Wang and Shakes (1997), indicating that both par-5 isoform selection and mRNA expression change during development.A progressive increase in PAR-5 protein levels could also be observed during embryogenesis, coincident with an increased contribution of par-5::utr.2. | ||
| Reference | WBPaper00045705 | ||
| Transgene | WBTransgene00020198 | ||
| WBTransgene00020199 | |||
| WBTransgene00020200 |
