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WormBase Tree Display for Expr_pattern: Expr1089

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Name Class

Expr1089Expression_ofGeneWBGene00003878
Reflects_endogenous_expression_ofWBGene00003878
Expression_dataLife_stageWBls:0000022
Anatomy_termWBbt:0003681Certain
WBbt:0003869Certain
WBbt:0003870Certain
WBbt:0005237Certain
GO_termGO:0043005
GO:0043025
Subcellular_localizationA fluorescence microscopy image with a standard fluorescein isothiocyanate filter showed AVAR and AVAL neuron cell bodies and the processes.
TypeReporter_gene
PatternAccording to the paper cgc3971: GFP was expressed exclusively in the interneuron AVA that is involved in the backward locomotion in C. elegans. The relative location of the GFP-positive neuron with that of the surrounding amphid neurons (ASK, ADL, ASI, ASH, and ASJ) establishes the identity of the GFP-expressing neuron as AVA. The GFP expression in these neurons was detected as early as L1 larva stage and persisted into the adult stage.
Also according to the same pers. comm.: ... the Rongo lab has tried to use the promoter fragment for opt-3 to drive expression in AVE specifically. In their hands, the opt-3 promoter is not as specific as we had observed. The Rongo lab see expression in AVEs and also the pharynx and in the touch cells...
But according to personal communication from Michael Krause on Sept 9, 2003 with WormBase curator: ... Turns out we were not correct, expression of this particular transgene was really in the neuron next door, AVE L&R. That information has been confirmed by David Miller and one other person and the transgene is used to show AVEs in WormAtlas...
PictureWBPicture0000008144
ReferenceWBPaper00003971
TransgeneWBTransgene00027338