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WormBase Tree Display for Expr_pattern: Expr1060

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Name Class

Expr1060Expression_ofGeneWBGene00004367
Reflects_endogenous_expression_ofWBGene00004367
Expression_dataLife_stageWBls:0000022
Anatomy_termWBbt:0003679Certain
WBbt:0005784Certain
GO_termGO:0005737
Subcellular_localizationRIC-8 staining in neuronal cell somas did not appear localized but instead appeared to fill the cytoplasm.
TypeAntibodyA polyclonal antibody against purified recombinant RIC-8.
PatternRIC-8 immunoreactivity observed throughout the nervous system in both juvenile and adult worms. In juveniles, but not adults, however, immunoreactivity was observed around the nuclei of many nonneuronal cells, including germ cell nuclei. Both neuronal and nonneuronal RIC-8 staining were absent in animals stained with a RIC-8 preabsorbed antibody preparation. Within the nervous system, RIC-8 appears to be present in most or all neurons, including those comprising the ventral nerve cord, although the amount of staining varied greatly between individual neurons. Observed RIC-8 staining in neuronal processes, including strong staining of amphid dendritic processes and weaker staining at some cholinergic synapses in the ventral nerve cord, as well as the axonal processes of the nerve ring.
PictureWBPicture0000009599
WBPicture0000009600
ReferenceWBPaper00004296
Antibody_infoWBAntibody00000300