WormBase Tree Display for Variation: WBVar02157213

WBVar02157213 Name: Public_name: av56
  Origin: Species: Caenorhabditis elegans
    Status: Live
  Affects: Gene: WBGene00003064
  Possibly_affects: WBGene00003064 Paper_evidence: WBPaper00061852
      Remark: CGC_name nfu-1
  Description: Phenotype: WBPhenotype:0000016 Paper_evidence: WBPaper00064917
        Curator_confirmed: WBPerson55803
        Recessive: Paper_evidence: WBPaper00064917
          Curator_confirmed: WBPerson55803
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00064917
            Curator_confirmed: WBPerson55803
        Affected_by: Molecule: WBMol:00003650 Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
        EQ_annotations: Life_stage: WBls:0000038 PATO:0000460 Paper_evidence: WBPaper00064917
                Curator_confirmed: WBPerson55803
        Phenotype_assay: Control_strain: WBStrain00000001 Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
      WBPhenotype:0000059 Paper_evidence: WBPaper00061852
        Curator_confirmed: WBPerson55803
      WBPhenotype:0000420 Paper_evidence: WBPaper00064917
        Curator_confirmed: WBPerson55803
        Recessive: Paper_evidence: WBPaper00064917
          Curator_confirmed: WBPerson55803
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00064917
            Curator_confirmed: WBPerson55803
        Affected_by: Molecule: WBMol:00004019 Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
        EQ_annotations: Life_stage: WBls:0000038 PATO:0000460 Paper_evidence: WBPaper00064917
                Curator_confirmed: WBPerson55803
        Phenotype_assay: Control_strain: WBStrain00000001 Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
      WBPhenotype:0000688 Paper_evidence: WBPaper00061852
        Curator_confirmed: WBPerson55803
      WBPhenotype:0001171 Paper_evidence: WBPaper00061852
        Curator_confirmed: WBPerson55803
      WBPhenotype:0001213 Paper_evidence: WBPaper00064917
        Curator_confirmed: WBPerson55803
        Remark: reduced motility Paper_evidence: WBPaper00064917
            Curator_confirmed: WBPerson55803
          reduced motility; partially rescued by avIs284 [myo-3p::nfu-1::unc-54 3'UTR] I Paper_evidence: WBPaper00064917
            Curator_confirmed: WBPerson55803
          reduced motility; partially rescued by avIs285 [rab-3p::nfu-1::rab-3 3'UTR] V Paper_evidence: WBPaper00064917
            Curator_confirmed: WBPerson55803
        Recessive: Paper_evidence: WBPaper00064917
          Curator_confirmed: WBPerson55803
        Rescued_by_transgene: WBTransgene00033591
          WBTransgene00033592
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00064917
            Curator_confirmed: WBPerson55803
        EQ_annotations: Life_stage: WBls:0000038 PATO:0000460 Paper_evidence: WBPaper00064917
                Curator_confirmed: WBPerson55803
        Phenotype_assay: Control_strain: WBStrain00000001 Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
            WBStrain00052841 Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
            WBStrain00052842 Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
          Genotype: avIs284 [myo-3p::nfu-1::unc-54 3 UTR] I Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
            avIs285 [rab-3p::nfu-1::rab-3 3 UTR] V Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
      WBPhenotype:0001502 Paper_evidence: WBPaper00064917
        Curator_confirmed: WBPerson55803
        Remark: piperazine resistant Paper_evidence: WBPaper00064917
            Curator_confirmed: WBPerson55803
        Recessive: Paper_evidence: WBPaper00064917
          Curator_confirmed: WBPerson55803
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00064917
            Curator_confirmed: WBPerson55803
        Affected_by: Molecule: WBMol:00004941 Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
        EQ_annotations: Life_stage: WBls:0000038 PATO:0000460 Paper_evidence: WBPaper00064917
                Curator_confirmed: WBPerson55803
        Phenotype_assay: Control_strain: WBStrain00000001 Paper_evidence: WBPaper00064917
              Curator_confirmed: WBPerson55803
      WBPhenotype:0001620 Paper_evidence: WBPaper00061852
        Curator_confirmed: WBPerson55803
      WBPhenotype:0001663 Paper_evidence: WBPaper00061852
        Curator_confirmed: WBPerson55803
      WBPhenotype:0002046 Paper_evidence: WBPaper00061852
        Curator_confirmed: WBPerson55803
  Disease_info: Models_disease: DOID:0080133
    Models_disease_in_annotation: WBDOannot00001084
  Reference: WBPaper00064917
    WBPaper00061852
  Remark: [2022-01-19T03:23:45.492Z WBPerson324] New Variation: WBPaper00061852; nfu-1(av56) [Gly166Cys] Curator_confirmed: WBPerson324
  Method: Allele