WormBase Tree Display for Variation: WBVar02148558
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| WBVar02148558 | Evidence | Paper_evidence | WBPaper00051305 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Name | Public_name | ac2 | |||||||
| Other_name | K09F5.2.1:c.2521G>C | ||||||||
| CE04746:p.Gly841Arg | |||||||||
| HGVSg | CHROMOSOME_X:g.7730518G>C | ||||||||
| Sequence_details | SMap | S_parent | Sequence | K09F5 | |||||
| Flanking_sequences | gaggctatccgcaaattcccaaccactctt | gacttccactcatcgtctctggaaagatcc | |||||||
| Mapping_target | K09F5 | ||||||||
| Type_of_mutation | Substitution | g | c | ||||||
| SeqStatus | Sequenced | ||||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00047208 | ||||||||
| Laboratory | AY | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00006925 | |||||||
| Transcript | K09F5.2.1 (12) | ||||||||
| Genetics | Interpolated_map_position | X | -1.31889 | ||||||
| Description | Phenotype | WBPhenotype:0001013 | Paper_evidence | WBPaper00051305 | |||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Remark | Enhanced susceptibility to P. aeruginosa PA14 killing | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Penetrance | Complete | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Dominant | Paper_evidence | WBPaper00051305 | |||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Phenotype_assay | Control_strain | WBStrain00034065 | Paper_evidence | WBPaper00051305 | |||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Genotype | zcIs4 [hsp-4::GFP] V | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| WBPhenotype:0001171 | Paper_evidence | WBPaper00051305 | |||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Remark | Reduced lifespan at 25°C. | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Penetrance | Complete | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Dominant | Paper_evidence | WBPaper00051305 | |||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| EQ_annotations | GO_term | GO:0008340 | PATO:0000460 | Paper_evidence | WBPaper00051305 | ||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Phenotype_assay | Control_strain | WBStrain00034065 | Paper_evidence | WBPaper00051305 | |||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Temperature | 25 | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Genotype | zcIs4 [hsp-4::GFP] V | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| WBPhenotype:0001485 | Paper_evidence | WBPaper00051305 | |||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Remark | ac2 is a dominant allele which causes upregulation of the ER stress reporter Phsp-4::GFP | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Penetrance | Complete | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Dominant | Paper_evidence | WBPaper00051305 | |||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| EQ_annotations | GO_term | GO:0034976 | PATO:0000460 | Paper_evidence | WBPaper00051305 | ||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Phenotype_assay | Control_strain | WBStrain00034065 | Paper_evidence | WBPaper00051305 | |||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Genotype | zcIs4 [hsp-4::GFP] V | Paper_evidence | WBPaper00051305 | ||||||
| Curator_confirmed | WBPerson36360 | ||||||||
| Reference | WBPaper00051305 | ||||||||
| Method | Substitution_allele |
