WormBase Tree Display for Variation: WBVar00275450

WBVar00275450 Name: Public_name: yz6
    Other_name: y26 Paper_evidence: WBPaper00033168
      B0212.5.1:c.974G>A
      CE20445:p.Trp325Ter
    HGVSg: CHROMOSOME_IV:g.3555543C>T
  Sequence_details: SMap: S_parent: Sequence: B0212
    Flanking_sequences: aaatgctggagattatgaaggtggagttct gaggttctcggatatgacgtgctccgcata
    Mapping_target: B0212
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00024918
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00023453
    Laboratory: JY
    Status: Live
  Affects: Gene: WBGene00003889
    Transcript: B0212.5.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: B0212.5.1:c.974G>A
        HGVSp: CE20445:p.Trp325Ter
        cDNA_position: 974
        CDS_position: 974
        Protein_position: 325
        Exon_number: 6/15
        Codon_change: tGg/tAg
        Amino_acid_change: W/*
  Genetics: Interpolated_map_position: IV -3.15579
  Description: Phenotype: WBPhenotype:0002378 Paper_evidence: WBPaper00058803
        Curator_confirmed: WBPerson36360
    Phenotype_not_observed: WBPhenotype:0001842 Paper_evidence: WBPaper00033168
        Curator_confirmed: WBPerson2021
        Remark: Similar to N2, Trifluoperazine produced a significant rebound response in the osm-9 mutants Paper_evidence: WBPaper00033168
            Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00033168
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: trifluoperazine (40 uM) Paper_evidence: WBPaper00033168
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00023954
    WBPaper00033168
    WBPaper00019327
    WBPaper00026130
    WBPaper00058803
  Remark: This allele has erroneously been referred to as "y26". Paper_evidence: WBPaper00033168
  Method: Substitution_allele