WormBase Tree Display for Variation: WBVar00251544

WBVar00251544 Name: Public_name: tm2698
    Other_name: Y37D8A.23b.1:c.992_1269del
      Y37D8A.23c.1:c.767_1038+6del
      Y37D8A.23a.1:c.992_1263+6del
      CE31832:p.Cys331PhefsTer6
    HGVSg: CHROMOSOME_III:g.12948239_12948516del
  Sequence_details: SMap: S_parent: Sequence: Y37D8A
    Flanking_sequences: tcatgggagcacttctccagtgctcggcat ttcggtgagcaattgccggtttgccaattt
    Mapping_target: Y37D8A
    Source_location: 7 CHROMOSOME_III 12948238 12948517 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm2698_external
      tm2698_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 2698
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00006762
    Transcript: Y37D8A.23c.1 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y37D8A.23c.1:c.767_1038+6del
        cDNA_position: 767-?
        CDS_position: 767-?
        Protein_position: 256-?
        Intron_number: 4/5
        Exon_number: 4/6
      Y37D8A.23b.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: Y37D8A.23b.1:c.992_1269del
        HGVSp: CE31832:p.Cys331PhefsTer6
        cDNA_position: 992-1269
        CDS_position: 992-1269
        Protein_position: 331-423
        Exon_number: 6/9
        Codon_change: tGCTTGTTCCGTCAGGATGGACTACTGTTCCAGTGTAATCAAATGTCGGCTGATTATCTATTCCAACAAGATAAACCGTACGATGTGAGCTTTGATACTGGAGATAAAGCCATTCAATGTGGACGGCACAATGATGTTTTCAAGCTTTGGTTGATGTGGAAGAGCAAGGGAATGGAGGGATATCGTCAGCAAATTAATAAGTTGATGGATTTGGCCAACTATTTTACCAGGAGAATTAAGGAAACTGAAGGATTTGAGTTGATTATTGAGAATGTGAGT/t
        Amino_acid_change: CLFRQDGLLFQCNQMSADYLFQQDKPYDVSFDTGDKAIQCGRHNDVFKLWLMWKSKGMEGYRQQINKLMDLANYFTRRIKETEGFELIIENVS/X
      Y37D8A.23a.1 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y37D8A.23a.1:c.992_1263+6del
        cDNA_position: 1002-?
        CDS_position: 992-?
        Protein_position: 331-?
        Intron_number: 7/9
        Exon_number: 7/10
  Isolation: Mutagen: TMP/UV
  Genetics: Map: III
  Description: Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as 'homozygous viable' by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
  Remark: 131324/131325-131602/131603 (278 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele