WormBase Tree Display for Variation: WBVar00250826

WBVar00250826 Name: Public_name: tm1863
    Other_name: B0041.2b.1:c.106-7_563del
      B0041.2d.1:c.106-7_563del
      B0041.2f.1:c.106-7_563del
      B0041.2e.1:c.106-7_563del
      B0041.2a.1:c.-21-7_437del
    HGVSg: CHROMOSOME_I:g.4655342_4656030del
  Sequence_details: SMap: S_parent: Sequence: B0041
    Flanking_sequences: ttggattctgttccataaaactcataacat gccaccatatggacaacgtggaaataatca
    Mapping_target: B0041
    Source_location: 7 CHROMOSOME_I 4655341 4656031 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm1863_external
      tm1863_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00054872
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 1863
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00015007
    Transcript: B0041.2f.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: B0041.2f.1:c.106-7_563del
        cDNA_position: ?-617
        CDS_position: ?-563
        Protein_position: ?-188
        Intron_number: 3-4/10
        Exon_number: 4-5/11
      B0041.2d.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: B0041.2d.1:c.106-7_563del
        cDNA_position: ?-563
        CDS_position: ?-563
        Protein_position: ?-188
        Intron_number: 2-3/8
        Exon_number: 3-4/9
      B0041.2c.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-464
        CDS_position: ?-437
        Protein_position: ?-146
        Intron_number: 2/8
        Exon_number: 1-3/9
      B0041.2e.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: B0041.2e.1:c.106-7_563del
        cDNA_position: ?-617
        CDS_position: ?-563
        Protein_position: ?-188
        Intron_number: 3-4/10
        Exon_number: 4-5/11
      B0041.2a.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-458
        CDS_position: ?-437
        Protein_position: ?-146
        Intron_number: 2/8
        Exon_number: 1-3/9
      B0041.2a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: B0041.2a.1:c.-21-7_437del
        cDNA_position: ?-617
        CDS_position: ?-437
        Protein_position: ?-146
        Intron_number: 2-4/10
        Exon_number: 3-5/11
      B0041.2g.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-460
        CDS_position: ?-437
        Protein_position: ?-146
        Intron_number: 2/8
        Exon_number: 1-3/9
      B0041.2b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: B0041.2b.1:c.106-7_563del
        cDNA_position: ?-623
        CDS_position: ?-563
        Protein_position: ?-188
        Intron_number: 3-4/10
        Exon_number: 4-5/11
    Interactor: WBInteraction000520792
      WBInteraction000521375
      WBInteraction000541261
      WBInteraction000541262
      WBInteraction000541263
      WBInteraction000541264
      WBInteraction000542499
  Isolation: Mutagen: TMP/UV
  Genetics: Map: I
  Description: Phenotype_not_observed: WBPhenotype:0000030 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. M. Han to the National Bioresource Project of Japan: WT growth. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000202 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. M. Han to the National Bioresource Project of Japan: WT adult alae. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000315 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. M. Han to the National Bioresource Project of Japan: WT touch response. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000518 Paper_evidence: WBPaper00031252
        Curator_confirmed: WBPerson712
        Remark: ain-2(tm1863) homozygous mutants displayed no discernable phenotype. Paper_evidence: WBPaper00031252
            Curator_confirmed: WBPerson712
      WBPhenotype:0000699 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. M. Han to the National Bioresource Project of Japan: WT vulval development. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0001887 Paper_evidence: WBPaper00031252
        Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: scm::GFP Paper_evidence: WBPaper00031252
              Curator_confirmed: WBPerson712
  Reference: WBPaper00031252
  Remark: 12204/12205-12893/12894 (689 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele