WormBase Tree Display for Variation: WBVar00249451

WBVar00249451 Name: Public_name: tm403
    Other_name: C09B8.7a.1:c.82-63_723+81delinsGATGCATGTGTTGCT
      C09B8.7b.1:c.82-63_714+81delinsGATGCATGTGTTGCT
    HGVSg: CHROMOSOME_X:g.6046948_6048421delinsAGCAACACATGCATC
  Sequence_details: SMap: S_parent: Sequence: C45B2
    Flanking_sequences: ttcctaaacctagaaataaaaaatgtggta aggggcaagcaacacatgcatcatctgatt
    Mapping_target: C45B2
    Source_location: 7 CHROMOSOME_X 6046947 6048422 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Insertion: agcaacacatgcatc
      Deletion
    PCR_product: tm403_external
      tm403_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 403
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00003911
      WBGene00196764
    Transcript: C09B8.7c.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        Intron_number: 1-5/9
        Exon_number: 1-5/10
      C09B8.7b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C09B8.7b.1:c.82-63_714+81delinsGATGCATGTGTTGCT
        Intron_number: 2-7/12
        Exon_number: 3-7/13
      C09B8.7a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C09B8.7a.1:c.82-63_723+81delinsGATGCATGTGTTGCT
        Intron_number: 2-7/12
        Exon_number: 3-7/13
      C45B2.10 VEP_consequence: non_coding_transcript_exon_variant
        VEP_impact: MODIFIER
        cDNA_position: 69-?
        Exon_number: 1/1
    Interactor: WBInteraction000518804
  Isolation: Mutagen: TMP/UV
  Genetics: Map: X
  Description: Phenotype: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Comment from Dr. Y. Jin: could not maintain as homozygote. Comment to the NBP from Dr. M. Labouesse: Development 136, 3109 (2009). Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
              CZ
              ML
      WBPhenotype:0000531 Paper_evidence: WBPaper00038193
        Curator_confirmed: WBPerson351
        Remark: Young L1 larvae are slightly short and have a head bump, which disappears by the middle of L1. The phenotype is not easy to spot Paper_evidence: WBPaper00038193
            Curator_confirmed: WBPerson351
        Temperature_sensitive: Cold_sensitive: Paper_evidence: WBPaper00038193
              Curator_confirmed: WBPerson351
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Comments to the NBP from Dr. Y. Jin: could not maintain as homozygote; Dr. M. Labouesse: Development 136, 3109 (2009). Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
              CZ
  Reference: WBPaper00038193
  Remark: 41185/41186-agcaacacatgcatc-42659/42660 (1474 bp deletion, 15 bp addition)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
    Old Mapping_target C09B8 updated based on the VEP analysis pipeline to C45B2.
  Method: NBP_knockout_allele