WormBase Tree Display for Variation: WBVar00144937

WBVar00144937 Evidence: Paper_evidence: WBPaper00026735
  Name: Public_name: e2706
    Other_name: CE28024:p.Gly1349Ile
      F39B2.4a.1:c.4039_4040delinsAT
      F39B2.4b.1:c.4045_4046delinsAT
      CE28023:p.Gly1347Ile
    HGVSg: CHROMOSOME_I:g.14779080_14779081delinsAT
  Sequence_details: SMap: S_parent: Sequence: F39B2
    Flanking_sequences: ttgttctacaattgcaaatatttcttcgcc agactttttgaggaatacggcgatcactga
    Mapping_target: F39B2
    Type_of_mutation: Substitution: gg at Paper_evidence: WBPaper00023901
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00006349
    Transcript: F39B2.4b.1 VEP_consequence: missense_variant
        VEP_impact: MODERATE
        HGVSc: F39B2.4b.1:c.4045_4046delinsAT
        HGVSp: CE28024:p.Gly1349Ile
        cDNA_position: 4052-4053
        CDS_position: 4045-4046
        Protein_position: 1349
        Exon_number: 16/19
        Codon_change: GGa/ATa
        Amino_acid_change: G/I
      F39B2.4a.1 VEP_consequence: missense_variant
        VEP_impact: MODERATE
        HGVSc: F39B2.4a.1:c.4039_4040delinsAT
        HGVSp: CE28023:p.Gly1347Ile
        cDNA_position: 4047-4048
        CDS_position: 4039-4040
        Protein_position: 1347
        Exon_number: 16/19
        Codon_change: GGa/ATa
        Amino_acid_change: G/I
  Genetics: Interpolated_map_position: I 26.8156
  Description: Phenotype (5)
    Phenotype_not_observed: WBPhenotype:0001212 Paper_evidence: WBPaper00026735
        Curator_confirmed: WBPerson48
        Remark: Based on a comparison of bleach sensitivity with wild type worms. Paper_evidence: WBPaper00026735
            Curator_confirmed: WBPerson48
      WBPhenotype:0001411 Paper_evidence: WBPaper00026735
        Curator_confirmed: WBPerson48
        Remark: Based on lectin binding properties to the cuticle Paper_evidence: WBPaper00026735
            Curator_confirmed: WBPerson48
        Phenotype_assay: Treatment: Tested the following fluorescein or rhodamine-conjugated lectins: WGA, SBA, TPA, PEA,, CON, LEA. Paper_evidence: WBPaper00026735
              Curator_confirmed: WBPerson48
      WBPhenotype:0001415 Paper_evidence: WBPaper00026735
        Curator_confirmed: WBPerson48
      WBPhenotype:0001420 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: No difference was observed between mutant and wild-type in terms of the amount of biofilm accumulated on the nose of the worm. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
  Reference: WBPaper00026735
    WBPaper00024311
    WBPaper00029153
  Method: Substitution_allele