WormBase Tree Display for Variation: WBVar00143071
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| WBVar00143071 | Name | Public_name | e262 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | |||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00003969 | ||||||||
| WBStrain00003971 | |||||||||
| WBStrain00004138 | |||||||||
| WBStrain00047362 | |||||||||
| Laboratory | CB | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00006773 | |||||||
| Interactor | WBInteraction000051786 | ||||||||
| WBInteraction000052168 | |||||||||
| WBInteraction000501658 | |||||||||
| WBInteraction000501676 | |||||||||
| WBInteraction000501678 | |||||||||
| WBInteraction000501927 | |||||||||
| WBInteraction000501929 | |||||||||
| WBInteraction000501930 | |||||||||
| WBInteraction000502818 | |||||||||
| WBInteraction000505069 | |||||||||
| WBInteraction000518429 | |||||||||
| WBInteraction000518432 | |||||||||
| WBInteraction000541784 | |||||||||
| WBInteraction000556944 | |||||||||
| WBInteraction000556948 | |||||||||
| WBInteraction000556951 | |||||||||
| WBInteraction000556954 | |||||||||
| WBInteraction000556958 | |||||||||
| WBInteraction000556961 | |||||||||
| WBInteraction000556963 | |||||||||
| WBInteraction000556965 | |||||||||
| WBInteraction000586280 | |||||||||
| Genetics | Mapping_data | In_2_point | 15 | ||||||
| In_multi_point | 32 | ||||||||
| 232 | |||||||||
| 237 | |||||||||
| 243 | |||||||||
| 251 | |||||||||
| 346 | |||||||||
| 1372 | |||||||||
| 1898 | |||||||||
| 1899 | |||||||||
| 2141 | |||||||||
| 2142 | |||||||||
| 2143 | |||||||||
| 2144 | |||||||||
| 2146 | |||||||||
| 2147 | |||||||||
| 2148 | |||||||||
| 2149 | |||||||||
| 2150 | |||||||||
| 2477 | |||||||||
| 2710 | |||||||||
| In_pos_neg_data | 4021 | ||||||||
| 4034 | |||||||||
| 4042 | |||||||||
| 4048 | |||||||||
| 4056 | |||||||||
| 4063 | |||||||||
| 4068 | |||||||||
| 5058 | |||||||||
| 5350 | |||||||||
| 6141 | |||||||||
| 6159 | |||||||||
| 6333 | |||||||||
| 6369 | |||||||||
| 6389 | |||||||||
| 6414 | |||||||||
| 6443 | |||||||||
| 6446 | |||||||||
| 6461 | |||||||||
| 6469 | |||||||||
| 6476 | |||||||||
| 6483 | |||||||||
| 6489 | |||||||||
| 6495 | |||||||||
| 6502 | |||||||||
| 6519 | |||||||||
| 6525 | |||||||||
| 6532 | |||||||||
| 6535 | |||||||||
| 6548 | |||||||||
| 6560 | |||||||||
| 6579 | |||||||||
| 6593 | |||||||||
| 6599 | |||||||||
| 6605 | |||||||||
| 6610 | |||||||||
| 6623 | |||||||||
| 6654 | |||||||||
| Description | Phenotype | WBPhenotype:0000164 | Paper_evidence | WBPaper00043908 | |||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0000324 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0000565 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | weak coiler; phenotype similar to Unc-4 | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Ease_of_scoring | ES2_Difficult_to_score | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000641 | Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | fairly active | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000643 | Paper_evidence | WBPaper00000031 | |||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPhenotype:0000688 | Paper_evidence | WBPaper00002829 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | sterile adult mutants had a normal life-span of two to three weeks and grew to the expected size for Unc-13 adults (0.6+/-0.8 mm) | Paper_evidence | WBPaper00002829 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Recessive | Paper_evidence | WBPaper00002829 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00002829 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Genotype | dpy-5 unc-13; sDp2 | Paper_evidence | WBPaper00002829 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001510 | Paper_evidence | WBPaper00036225 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Misspecification of a specific class of ventral cord motorneurons: Mutants show ectopic expression of the wdIs3 (del-1::gfp) reporter in the presumptive VA motoneurons. The reporter is expressed only in the VB motoneurons in wildtype animals at the L2 stage. | Paper_evidence | WBPaper00036225 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00036225 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005300 | PATO:0000460 | Paper_evidence | WBPaper00036225 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001660 | Paper_evidence | WBPaper00006052 | |||||||
| WBPaper00036225 | |||||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | ASE asymmetry is disrupted (as seen with lim-6, gcy-5 and gcy-7 reporters). 2 ASEL | Paper_evidence | WBPaper00006052 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Lsy phenotype - 2ASEL | Paper_evidence | WBPaper00036225 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Penetrance | Incomplete | Paper_evidence | WBPaper00006052 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00006052 | ||||||
| WBPaper00036225 | |||||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005663 | PATO:0000460 | Paper_evidence | WBPaper00006052 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBbt:0003903 | PATO:0000460 | Paper_evidence | WBPaper00036225 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00006052 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Genotype | otIs6, otIs114,otIs3, ntIs1 | Paper_evidence | WBPaper00006052 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001716 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002284 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002288 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002293 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002295 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002300 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002301 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002310 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002312 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002323 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002328 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002336 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002344 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0002345 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0004023 | Paper_evidence | WBPaper00043908 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Phenotype_not_observed | WBPhenotype:0000097 | Paper_evidence | WBPaper00030973 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | No ectopic ASEL cell is derived from ABara (Data not shown). | Paper_evidence | WBPaper00030973 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00030973 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00030973 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00030973 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Treatment | Laser ablation of ABp blastomere in e262 mutant embryos expressing an ASEL marker | Paper_evidence | WBPaper00030973 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Temperature | 25C | Paper_evidence | WBPaper00030973 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000384 | Paper_evidence | WBPaper00037678 | |||||||
| Curator_confirmed | WBPerson557 | ||||||||
| Remark | unc-37(e262) mutants exhibit normal axon guidance where all commissures reach the dorsal nerve cord. | Paper_evidence | WBPaper00037678 | ||||||
| Curator_confirmed | WBPerson557 | ||||||||
| Phenotype_assay | Genotype | unc-25::gfp | Paper_evidence | WBPaper00037678 | |||||
| Curator_confirmed | WBPerson557 | ||||||||
| WBPhenotype:0000670 | Paper_evidence | WBPaper00002829 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | none of the sterile mutants were rescued by wild-type sperm, thereforenone of them had defects in spermatogenesis alone. | Paper_evidence | WBPaper00002829 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Recessive | Paper_evidence | WBPaper00002829 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00002829 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Genotype | dpy-5 unc-13; sDp2 | Paper_evidence | WBPaper00002829 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001661 | Paper_evidence | WBPaper00006052 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | No disruption of AWC asymmetry (as seen with str-2 reporter) | Paper_evidence | WBPaper00006052 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00006052 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00006052 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Genotype | kyIs140 | Paper_evidence | WBPaper00006052 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Reference | WBPaper00043908 | ||||||||
| WBPaper00027237 | |||||||||
| WBPaper00002829 | |||||||||
| WBPaper00010528 | |||||||||
| WBPaper00000031 | |||||||||
| WBPaper00006052 | |||||||||
| WBPaper00010445 | |||||||||
| WBPaper00023402 | |||||||||
| WBPaper00030973 | |||||||||
| WBPaper00024162 | |||||||||
| WBPaper00012694 | |||||||||
| WBPaper00011060 | |||||||||
| WBPaper00014383 | |||||||||
| WBPaper00022665 | |||||||||
| WBPaper00002798 | |||||||||
| WBPaper00022186 | |||||||||
| WBPaper00011052 | |||||||||
| WBPaper00022498 | |||||||||
| WBPaper00022335 | |||||||||
| WBPaper00011049 | |||||||||
| WBPaper00014722 | |||||||||
| WBPaper00022541 | |||||||||
| WBPaper00024161 | |||||||||
| WBPaper00023157 | |||||||||
| WBPaper00036225 | |||||||||
| WBPaper00037678 | |||||||||
| Method | Allele |
