WormBase Tree Display for Variation: WBVar00094849

WBVar00094849 Evidence: Paper_evidence: WBPaper00030973
  Name: Public_name: ot123
  Sequence_details: Mapping_target: R03C1
    Type_of_mutation: Deletion
    SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00029370
    Laboratory: OH
    Status: Live
  Affects: Gene: WBGene00000584
  Description: Phenotype: WBPhenotype:0001660 Paper_evidence: WBPaper00030973
          WBPaper00044621
        Curator_confirmed: WBPerson2021
          WBPerson6538
        Remark: ASE asymmetry is disrupted. 2 ASER Paper_evidence: WBPaper00030973
            Curator_confirmed: WBPerson2021
          Fig 3B, C. Loss of ASE asymmetry Paper_evidence: WBPaper00044621
            Curator_confirmed: WBPerson6538
        Penetrance: High: 48 percent of ot123 heterozygotes are 2 ASER. 100 percent of ot123 homozygotes are 2 ASER Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
              Paper_evidence: WBPaper00044621
              Curator_confirmed: WBPerson6538
        Semi_dominant: Paper_evidence: WBPaper00030973
          Curator_confirmed: WBPerson2021
        Variation_effect: Hypermorph_gain_of_function: Paper_evidence: WBPaper00030973
              WBPaper00044621
            Curator_confirmed: WBPerson2021
              WBPerson6538
        EQ_annotations: Anatomy_term: WBbt:0005663 PATO:0000460 Paper_evidence: WBPaper00030973
                  WBPaper00044621
                Curator_confirmed: WBPerson2021
                  WBPerson6538
        Phenotype_assay: Temperature: 25C Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
          Genotype: otIs114 [lim-6p::GFP], ntIs1 [ gcy-5p::GFP] Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00030973
    WBPaper00044621
  Method: Deletion_allele