WormBase Tree Display for Variation: WBVar00092782

WBVar00092782 Evidence: Paper_evidence: WBPaper00031230
  Name: Public_name: ok1573
    HGVSg: CHROMOSOME_IV:g.9682216_9683114del
  Sequence_details: SMap: S_parent: Sequence: ZK1251
    Flanking_sequences: gattcgcatgcttttccacaaaccgcaaac cttatcaagcagttgtgcggtttcttgatc
    Mapping_target: ZK1251
    Type_of_mutation: Deletion
    PCR_product: ok1573_external
      ok1573_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00032086
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00002090
      WBGene00189968
      WBGene00014240
    Transcript: ZK1251.2b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-258
        CDS_position: ?-239
        Protein_position: ?-80
        Intron_number: 2/4
        Exon_number: 1-3/5
      ZK1251.14 VEP_consequence: transcript_ablation
        VEP_impact: HIGH
        Exon_number: 1/1
      ZK1251.2a.1 VEP_consequence: coding_sequence_variant,5_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: ?-206
        CDS_position: ?-206
        Protein_position: ?-69
        Exon_number: 1/3
      ZK1251.1.1 VEP_consequence: coding_sequence_variant,3_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: 352-?
        CDS_position: 340-?
        Protein_position: 114-?
        Exon_number: 3-4/4
  Isolation: Mutagen: UV/TMP
  Description: Phenotype: WBPhenotype:0000061 Paper_evidence: WBPaper00031230
        Curator_confirmed: WBPerson712
        Remark: Mean lifespan is extended (21.4 0.7 (n = 124/186), P < 0.0001) compared to N2 (14.3 0.3 (n = 176/215; events/total)). Paper_evidence: WBPaper00031230
            Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: Strain was outcrossed 3 times to N2 before testing. Paper_evidence: WBPaper00031230
              Curator_confirmed: WBPerson712
          Temperature: 20C Paper_evidence: WBPaper00031230
              Curator_confirmed: WBPerson712
  Reference: WBPaper00031230
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele