WormBase Tree Display for Variation: WBVar00091430

WBVar00091430 Evidence: Paper_evidence: WBPaper00031872
  Name: Public_name: nu468
    Other_name (12)
    HGVSg: CHROMOSOME_I:g.5548479_5548480delinsAA
  Sequence_details: SMap: S_parent: Sequence: M01A10
    Flanking_sequences: tagtatacgacaagggaatagttgttcaat aatttaggaacaagagaagttgatcgatat
    Mapping_target: M01A10
    Type_of_mutation: Substitution: gg rr Paper_evidence: WBPaper00031872
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: KP
    Status: Live
  Affects: Gene: WBGene00006594
    Transcript: M01A10.2g.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: M01A10.2g.1:c.635_636delinsAA
        HGVSp: CE50290:p.Trp212Ter
        cDNA_position: 742-743
        CDS_position: 635-636
        Protein_position: 212
        Exon_number: 7/26
        Codon_change: tGG/tAA
        Amino_acid_change: W/*
      M01A10.2f.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: M01A10.2f.1:c.635_636delinsAA
        HGVSp: CE41686:p.Trp212Ter
        cDNA_position: 744-745
        CDS_position: 635-636
        Protein_position: 212
        Exon_number: 7/26
        Codon_change: tGG/tAA
        Amino_acid_change: W/*
      M01A10.2i.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: M01A10.2i.1:c.635_636delinsAA
        HGVSp: CE50363:p.Trp212Ter
        cDNA_position: 635-636
        CDS_position: 635-636
        Protein_position: 212
        Exon_number: 6/24
        Codon_change: tGG/tAA
        Amino_acid_change: W/*
      M01A10.2h.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: M01A10.2h.1:c.635_636delinsAA
        HGVSp: CE50232:p.Trp212Ter
        cDNA_position: 742-743
        CDS_position: 635-636
        Protein_position: 212
        Exon_number: 7/25
        Codon_change: tGG/tAA
        Amino_acid_change: W/*
      M01A10.2e.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: M01A10.2e.1:c.635_636delinsAA
        HGVSp: CE41685:p.Trp212Ter
        cDNA_position: 741-742
        CDS_position: 635-636
        Protein_position: 212
        Exon_number: 7/26
        Codon_change: tGG/tAA
        Amino_acid_change: W/*
      M01A10.2a.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: M01A10.2a.1:c.635_636delinsAA
        HGVSp: CE40307:p.Trp212Ter
        cDNA_position: 742-743
        CDS_position: 635-636
        Protein_position: 212
        Exon_number: 7/25
        Codon_change: tGG/tAA
        Amino_acid_change: W/*
  Isolation: Mutagen: EMS Paper_evidence: WBPaper00026714
  Genetics: Interpolated_map_position: I 0.108099
  Description: Phenotype: WBPhenotype:0000016 Paper_evidence: WBPaper00031872
        Curator_confirmed: WBPerson712
        Remark: % animals paralyzed after 60 min on 1mM aldicarb was significantly higher than % N2 animals paralyzed. Paper_evidence: WBPaper00031872
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003650 Paper_evidence: WBPaper00031872
              Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0007833 PATO:0001549 Paper_evidence: WBPaper00031872
                Curator_confirmed: WBPerson712
      WBPhenotype:0000420 Paper_evidence: WBPaper00031872
        Curator_confirmed: WBPerson712
        Remark: % animals paralyzed after 60 min on 200mM levamisole was significantly higher than % N2 animals paralyzed under same conditions. Paper_evidence: WBPaper00031872
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00004019 Paper_evidence: WBPaper00031872
              Curator_confirmed: WBPerson712
  Reference: WBPaper00031872
  Remark: Manually curated Gene associations preserved as a text remark so that VEP is the canonical predictor of consequence: WBGene00006594 Amber_UAG_or_Opal_UGA W(212) to stop Paper_evidence: WBPaper00026714
  Method: Substitution_allele