WormBase Tree Display for Variation: WBVar00087786

WBVar00087786 Evidence: Paper_evidence: WBPaper00024329
  Name: Public_name: hc88
    Other_name: hc88ts
      C17D12.6a.1:c.773G>A
      CE27074:p.Cys258Tyr
    HGVSg: CHROMOSOME_I:g.11584549C>T
  Sequence_details: SMap: S_parent: Sequence: C17D12
    Flanking_sequences: tgaatttcagaaaaatttcaggtgaaaact cgaaacccttcaaattccttcaacagcccc
    Mapping_target: C17D12
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00024329
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00000377
      WBStrain00034899
      WBStrain00034903
      WBStrain00034904
      WBStrain00034905
    Laboratory: BA
    Status: Live
  Affects: Gene: WBGene00004963
      WBGene00305275
    Transcript: C17D12.6a.1 (12)
      C17D12.19
  Genetics: Interpolated_map_position: I 9.27266
    Mapping_data: In_multi_point: 3107
  Description: Phenotype: WBPhenotype:0000357 Paper_evidence: WBPaper00001075
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001075
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001075
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 16C, 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000693 Paper_evidence: WBPaper00001075
        Curator_confirmed: WBPerson2021
        Remark: At 25C, males fail to sire progeny in mating experiments Paper_evidence: WBPaper00001075
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001075
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00001075
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001360 Paper_evidence: WBPaper00001075
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001075
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001075
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 16C, 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001720 Paper_evidence: WBPaper00001075
        Curator_confirmed: WBPerson2021
        Remark: Spermatozoa are slowly swept out of the spermatheca by passing oocytes Paper_evidence: WBPaper00001075
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001075
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001075
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 16C, 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000390 Paper_evidence: WBPaper00001075
        Curator_confirmed: WBPerson2021
        Remark: Adults produce large numbers of spermatids that activate in vitro after pronase treatment to form spermatozoa that are cytologically indistinguishable from wild type Paper_evidence: WBPaper00001075
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001075
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00001075
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 16C, 25C Paper_evidence: WBPaper00001075
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00001075
    WBPaper00065353
  Method: Substitution_allele