WormBase Tree Display for Variation: WBVar00000370

WBVar00000370 Name: Public_name: b244
  Sequence_details: SeqStatus: Not_sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00005815
    Laboratory: DH
    Status: Live
  Affects: Gene: WBGene00006994
    Interactor: WBInteraction000052186
      WBInteraction000501450
  Genetics: Mapping_data: In_2_point: 546
      In_multi_point: 475
        1389
  Description: Phenotype: WBPhenotype:0000052 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: maternal effect embryonic lethal after larval shift-up Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0000164 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0000351 Paper_evidence: WBPaper00032438
        Curator_confirmed: WBPerson712
      WBPhenotype:0000353 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0000759 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: meiotic and mitotic spindle abnormalities, defects in first mitotic divisions, like mei-1(gf), mel-26(gf) Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0000762 Paper_evidence: WBPaper00030892
        Curator_confirmed: WBPerson712
        Remark: The spindle is displaced to the posterior of the one cell embryo, similar in effect to nocodazole treatment. Paper_evidence: WBPaper00030892
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000006 PATO:0000460 Paper_evidence: WBPaper00030892
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: zuIs45[NMY-2::GFP] Paper_evidence: WBPaper00030892
              Curator_confirmed: WBPerson712
      WBPhenotype:0000961 Paper_evidence: WBPaper00039860
        Curator_confirmed: WBPerson712
        Remark: NMY-2::GFP foci in the vicinity of the posterior spindle in zyg-9(b244ts) embryos are dim and fail to coalesce. Paper_evidence: WBPaper00039860
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00039860
              Curator_confirmed: WBPerson712
      WBPhenotype:0001129 Paper_evidence: WBPaper00039860
        Curator_confirmed: WBPerson712
        Remark: Anterior furrows ingress to 40% of the width of the embryo in zyg-9(b244ts) embryos. Paper_evidence: WBPaper00039860
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00039860
              Curator_confirmed: WBPerson712
      WBPhenotype:0001153 Paper_evidence: WBPaper00039860
        Curator_confirmed: WBPerson712
        Remark: Upon fertilization of zyg-9(b244ts) embryos at the non-permissive temperature (25 deg C), migration of the female pronucleus toward the male pronucleus fails and the female and male pronuclei remain in the anterior and posterior poles, respectively. Paper_evidence: WBPaper00039860
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Paper_evidence: WBPaper00039860
              Curator_confirmed: WBPerson712
      WBPhenotype:0002286 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002289 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002295 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002300 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002303 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002328 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002335 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
      WBPhenotype:0002501 Paper_evidence: WBPaper00030892
        Curator_confirmed: WBPerson712
        Remark: Two cleavage furrows are formed, a posterior furrow that bisects the misplaced spindle and an anterior spindle, which forms at a distance from the spindle, similar in effect to nocodazole treatment. Paper_evidence: WBPaper00030892
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000006 PATO:0000460 Paper_evidence: WBPaper00030892
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: zuIs45[NMY-2::GFP] Paper_evidence: WBPaper00030892
              Curator_confirmed: WBPerson712
      WBPhenotype:0004025 Paper_evidence: WBPaper00043908
        Curator_confirmed: WBPerson2987
  Reference: WBPaper00039860
    WBPaper00043908
    WBPaper00030892
    WBPaper00015917
    WBPaper00016431
    WBPaper00032438
    WBPaper00016160
    WBPaper00016208
    WBPaper00016581
    WBPaper00001532
    WBPaper00029464
  Method: Allele