WormBase Tree Display for Variation: WBVar00000063

WBVar00000063 Evidence: Paper_evidence: WBPaper00002466
  Name: Public_name: ad805
    Other_name: M01D7.7a.1:c.247-1G>A
      M01D7.7b.1:c.91-1G>A
    HGVSg: CHROMOSOME_I:g.1838779G>A
  Sequence_details: SMap: S_parent: Sequence: M01D7
    Flanking_sequences: gaagccttaaaattcgaactattttttcca tctatgatacgagcgatggacacattagat
    Mapping_target: M01D7
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00002466
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00005520
    Laboratory: DA
    Status: Live
  Affects: Gene: WBGene00001196
    Transcript: M01D7.7b.1 VEP_consequence: splice_acceptor_variant
        VEP_impact: HIGH
        HGVSc: M01D7.7b.1:c.91-1G>A
        Intron_number: 2/8
      M01D7.7a.1 VEP_consequence: splice_acceptor_variant
        VEP_impact: HIGH
        HGVSc: M01D7.7a.1:c.247-1G>A
        Intron_number: 3/9
    Interactor: WBInteraction000518669
  Genetics: Interpolated_map_position: I -12.5567
    Mapping_data: In_2_point: 6155
      In_multi_point: 2661
  Description: Phenotype: WBPhenotype:0000006 Paper_evidence: WBPaper00002305
        Curator_confirmed: WBPerson557
        Semi_dominant: Paper_evidence: WBPaper00002305
          Curator_confirmed: WBPerson557
      WBPhenotype:0000022 Paper_evidence: WBPaper00002305
        Curator_confirmed: WBPerson557
      WBPhenotype:0000153 Paper_evidence: WBPaper00002305
        Curator_confirmed: WBPerson557
      WBPhenotype:0000205 Paper_evidence: WBPaper00002305
        Curator_confirmed: WBPerson557
        Semi_dominant: Paper_evidence: WBPaper00002305
          Curator_confirmed: WBPerson557
      WBPhenotype:0000397 Paper_evidence: WBPaper00032087
        Curator_confirmed: WBPerson2021
        Remark: Animals are essentially unresponsive to harsh physical stimulation Paper_evidence: WBPaper00032087
            Curator_confirmed: WBPerson2021
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00032087
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000643 Paper_evidence: WBPaper00002305
        Curator_confirmed: WBPerson557
      WBPhenotype:0000644 Paper_evidence: WBPaper00032087
          WBPaper00002305
        Curator_confirmed: WBPerson2021
          WBPerson557
        Remark: Animals are nearly paralyzed Paper_evidence: WBPaper00032087
            Curator_confirmed: WBPerson2021
          Flaccid paralysis. Paper_evidence: WBPaper00002305
            Curator_confirmed: WBPerson557
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00032087
            Curator_confirmed: WBPerson2021
      WBPhenotype:0001413 Paper_evidence: WBPaper00040813
        Curator_confirmed: WBPerson2706
      WBPhenotype:0001645 Paper_evidence: WBPaper00040284
        Curator_confirmed: WBPerson2987
        Remark: Table 1 Paper_evidence: WBPaper00040284
            Curator_confirmed: WBPerson2987
      WBPhenotype:0001897 Paper_evidence: WBPaper00032087
        Curator_confirmed: WBPerson2021
        Remark: Exposure to blue-violet light resulted in a 3.5 fold increase in the locomotion rates of wild-type. However, the locomotion rate of egl-30 mutants upon blue-violet light exposure was not significantly different from the basal rate of wild-type animals. Paper_evidence: WBPaper00032087
            Curator_confirmed: WBPerson2021
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00032087
            Curator_confirmed: WBPerson2021
      WBPhenotype:0002378 Paper_evidence: WBPaper00040813
        Curator_confirmed: WBPerson2706
  Reference: WBPaper00040284
    WBPaper00040813
    WBPaper00014715
    WBPaper00017502
    WBPaper00026249
    WBPaper00002466
    WBPaper00032087
    WBPaper00002305
    WBPaper00065992
  Method: Substitution_allele