Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Variation: WBVar00088387

expand all nodes | collapse all nodes | view schema

Name Class

WBVar00088387EvidencePaper_evidenceWBPaper00002930
NamePublic_nameky10
Other_nameB0212.5.1:c.517C>T
CE20445:p.Gln173Ter
HGVSgCHROMOSOME_IV:g.3556045G>A
Sequence_detailsSMapS_parentSequenceB0212
Flanking_sequencesGCGGCCTGAAACATTGTGTTATCTTTAGGCAATCAGCCCTCCACCTAGCCATTGTACACG
Mapping_targetB0212
Type_of_mutationSubstitutionctPaper_evidenceWBPaper00002930
Person_evidenceWBPerson40923
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00005214
WBStrain00007483
WBStrain00052609
LaboratoryCX
StatusLive
AffectsGeneWBGene00003889
TranscriptB0212.5.1VEP_consequencestop_gained,splice_region_variant
VEP_impactHIGH
HGVScB0212.5.1:c.517C>T
HGVSpCE20445:p.Gln173Ter
cDNA_position517
CDS_position517
Protein_position173
Exon_number5/15
Codon_changeCaa/Taa
Amino_acid_changeQ/*
Interactor (17)
GeneticsInterpolated_map_positionIV-3.15548
DescriptionPhenotype (34)
Phenotype_not_observedWBPhenotype:0000302Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Variation_effectNullPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Phenotype_assayTreatment1:200 dilution of benzaldehydePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
WBPhenotype:0000304Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Variation_effectNullPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Phenotype_assayTreatment1:100 dilution of isoamyl alcoholPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
WBPhenotype:0000306Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RemarkAWA specific expression of odr-7::GFP is unaltered in osm-9 mutantsPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Variation_effectNullPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Phenotype_assayGenotypekyIs38Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
WBPhenotype:0000398Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RemarkMutants respond to stroking to the body with a hairPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Variation_effectNullPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
WBPhenotype:0000481Paper_evidenceWBPaper00065019
Curator_confirmedWBPerson712
Remarkosm-9 mutants (osm-9: solvent vs Argentine ant extract, t(40) = 1.434, p = 0.239). Within groups exposed to Argentine ant compounds, the response of osm-9 mutants was significantly different from both PD1074 (t(40) = 2.990, p = 0.010) and tax-4 mutants (t(40) = 3.189, p = 0.006).Paper_evidenceWBPaper00065019
Curator_confirmedWBPerson712
Extracts of the Velvety tree ant showed a different pattern of behavioral response, in which tax-4 mutants were repelled by the extracts (tax-4: solvent vs Velvety tree ant extract, t(40) = 5.645, p < 0.001), but osm-9 mutants (osm-9: solvent vs Velvety tree ant extract, t(40) = 0.018, p = 0.985) and the wild type (PD1074: solvent vs Velvety tree ant extract, t(40) = 1.096, p = 0.373) were not.Paper_evidenceWBPaper00065019
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00008002Paper_evidenceWBPaper00065019
Curator_confirmedWBPerson712
WBMol:00008001Paper_evidenceWBPaper00065019
Curator_confirmedWBPerson712
WBPhenotype:0000630Paper_evidenceWBPaper00035961
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00003904Paper_evidenceWBPaper00035961
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005665PATO:0000460Paper_evidenceWBPaper00035961
Curator_confirmedWBPerson712
WBPhenotype:0000905Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RemarkThe morphology of AWA and ASH neurons is normalPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Variation_effectNullPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
EQ_annotationsAnatomy_termWBbt:0005670PATO:0000460Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
WBbt:0005665PATO:0000460Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
WBPhenotype:0001084Paper_evidenceWBPaper00005150
Curator_confirmedWBPerson48
Phenotype_assayTreatmentChemotaxis assay for a 10 minute timepoint.Paper_evidenceWBPaper00005150
Curator_confirmedWBPerson48
WBPhenotype:0001085Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Variation_effectNullPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Phenotype_assayTreatment1:1000 dilution of butanonePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
WBPhenotype:0001086Paper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Variation_effectNullPaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
Phenotype_assayTreatment1:1000 dilution of trimethylthiazolePaper_evidenceWBPaper00002930
Curator_confirmedWBPerson2021
WBPhenotype:0001435Paper_evidenceWBPaper00005150
Curator_confirmedWBPerson48
Phenotype_assayTreatmentChemotaxis assay for a 10 minute timepoint.Paper_evidenceWBPaper00005150
Curator_confirmedWBPerson48
WBPhenotype:0001442Paper_evidenceWBPaper00005150
Curator_confirmedWBPerson48
Phenotype_assayTreatmentChemotaxis assay for a 10 minute timepoint.Paper_evidenceWBPaper00005150
Curator_confirmedWBPerson48
WBPhenotype:0001454Paper_evidenceWBPaper00059946
Curator_confirmedWBPerson712
RemarkIndividual loss of neither OSM-9 nor OCR-2 function affected response to 10mM quinine (Figure 1A), similar to our previous report (Ezak et al. 2010). Further, osm-9 and ocr-2 single mutants responded similarly to wild-type animals across the range of quinine concentrations tested (10mM - 1mM, Figure 1A).Paper_evidenceWBPaper00059946
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00003904Paper_evidenceWBPaper00059946
Curator_confirmedWBPerson712
WBPhenotype:0001469Paper_evidenceWBPaper00032215
Curator_confirmedWBPerson712
RemarkAnimals exhibited attraction to butanone similar to wild-type animals.Paper_evidenceWBPaper00032215
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00005086Paper_evidenceWBPaper00032215
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005665PATO:0000460Paper_evidenceWBPaper00032215
Curator_confirmedWBPerson712
WBbt:0005661PATO:0000460Paper_evidenceWBPaper00032215
Curator_confirmedWBPerson712
WBPhenotype:0001484Paper_evidenceWBPaper00005150
Curator_confirmedWBPerson48
Phenotype_assayTreatmentChemotaxis assay for a 10 minute timepoint.Paper_evidenceWBPaper00005150
Curator_confirmedWBPerson48
WBPhenotype:0001741Paper_evidenceWBPaper00032000
Curator_confirmedWBPerson712
Remark<10% males displayed spontaneous spicule-muscle seizures in the presence or absence of food.Paper_evidenceWBPaper00032000
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005826PATO:0000460Paper_evidenceWBPaper00032000
Curator_confirmedWBPerson712
WBbt:0005312PATO:0000460Paper_evidenceWBPaper00032000
Curator_confirmedWBPerson712
Life_stageWBls:0000056PATO:0000460Paper_evidenceWBPaper00032000
Curator_confirmedWBPerson712
Phenotype_assayTreatmentTo effect food deprivation animals were moved to plates with no food (E. coli) or fed inedible bacteria (aztreonam-treated E. coli).Paper_evidenceWBPaper00032000
Curator_confirmedWBPerson712
WBPhenotype:0001765Paper_evidenceWBPaper00031935
WBPaper00031936
Curator_confirmedWBPerson712
WBPerson2021
RemarkCarbon dioxide avoidance (Cdad) was not defective in the presence or absence of food.Paper_evidenceWBPaper00031935
Curator_confirmedWBPerson712
Mutants respond normally to CO2Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
Phenotype_assayTreatmentStrains were maintained at 22C. Animals were exposed to a 5% to 0% CO2 gradient.Paper_evidenceWBPaper00031935
Curator_confirmedWBPerson712
10% CO2Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
WBPhenotype:0001780Paper_evidenceWBPaper00029060
Curator_confirmedWBPerson2021
RemarkMutants show normal butanone enhancementPaper_evidenceWBPaper00029060
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00029060
Curator_confirmedWBPerson2021
Phenotype_assayTreatmentPreexposure to 1:10 dilution of butanone and food. Animals were then subjected to odorant chemotaxis assays and/or selection assaysPaper_evidenceWBPaper00029060
Curator_confirmedWBPerson2021
WBPhenotype:0001939Paper_evidenceWBPaper00035961
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00003731Paper_evidenceWBPaper00035961
Curator_confirmedWBPerson712
WBMol:00003904Paper_evidenceWBPaper00035961
Curator_confirmedWBPerson712
WBMol:00003565Paper_evidenceWBPaper00035961
Curator_confirmedWBPerson712
WBMol:00001530Paper_evidenceWBPaper00035961
Curator_confirmedWBPerson712
WBMol:00005022Paper_evidenceWBPaper00035961
Curator_confirmedWBPerson712
ReferenceWBPaper00002930
WBPaper00038142
WBPaper00043908
WBPaper00031936
WBPaper00031935
WBPaper00029060
WBPaper00032000
WBPaper00023490
WBPaper00005150
WBPaper00017785
WBPaper00019186
WBPaper00032215
WBPaper00035961
WBPaper00037771
WBPaper00043891
WBPaper00048410
WBPaper00059397
WBPaper00059946
WBPaper00060627
WBPaper00045595
WBPaper00061840
WBPaper00061945
WBPaper00064938
WBPaper00064927
WBPaper00065019
RemarkManually curated Gene associations preserved as a text remark so that VEP is the canonical predictor of consequence: WBGene00003889 Ochre_UAA Q(173) to stopPaper_evidenceWBPaper00002930
MethodSubstitution_allele