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WormBase Tree Display for Variation: WBVar00143953

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Name Class

WBVar00143953EvidencePerson_evidenceWBPerson25803
NamePublic_namee1376
Other_nameCE50691:p.Pro423GlnfsTer51
F25E2.5e.1:c.1511del
CE50852:p.Pro426GlnfsTer51
CE26364:p.Pro439GlnfsTer51
F25E2.5c.1:c.1316del
F25E2.5h.1:c.1268del
F25E2.5b.1:c.1520del
F25E2.5f.1:c.1502del
F25E2.5g.1:c.1277del
CE28003:p.Pro501GlnfsTer51
CE30963:p.Pro507GlnfsTer51
CE28002:p.Pro535GlnfsTer51
CE50732:p.Pro504GlnfsTer51
F25E2.5d.1:c.1613del
F25E2.5a.1:c.1604del
CE50706:p.Pro538GlnfsTer51
HGVSgCHROMOSOME_X:g.822069del
Sequence_detailsSMapS_parentSequenceF25E2
Flanking_sequencesACCATACGTCCCAACAAGGCAGTCATCAACAGGGCACCAAGGTCAGGTACCGAATGATCC
Mapping_targetF25E2
Type_of_mutationDeletion
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00004312
WBStrain00004377
WBStrain00026945
WBStrain00030757
WBStrain00035151
LaboratoryCB
StatusLive
Affects (3)
GeneticsInterpolated_map_positionX-19.4991
Mapping_dataIn_2_point299
413
414
DescriptionPhenotype (17)
Phenotype_not_observedWBPhenotype:0000061Paper_evidenceWBPaper00005086
Curator_confirmedWBPerson712
Phenotype_assayTemperature15CPaper_evidenceWBPaper00005086
Curator_confirmedWBPerson712
WBPhenotype:0000256Paper_evidenceWBPaper00000316
Curator_confirmedWBPerson712
WBPhenotype:0000306Paper_evidenceWBPaper00032073
Curator_confirmedWBPerson712
RemarkThe expression of cuIs5 (or cuIs2), a reporter of TGF-beta -signaling activity, remains at wild type levels.Paper_evidenceWBPaper00032073
Curator_confirmedWBPerson712
Phenotype_assayGenotypecuIs5 or cuIs2Paper_evidenceWBPaper00032073
Curator_confirmedWBPerson712
WBPhenotype:0000520Paper_evidenceWBPaper00000316
Curator_confirmedWBPerson712
WBPhenotype:0000660Paper_evidenceWBPaper00005511
Curator_confirmedWBPerson2021
Remarkdaf-3 mutants do not aggregate and border on foodPaper_evidenceWBPaper00005511
Curator_confirmedWBPerson2021
WBPhenotype:0000823Paper_evidenceWBPaper00035610
Curator_confirmedWBPerson2021
RemarkThe mitotic region of daf-3(e1376) was indistinguishable from that of the wild typePaper_evidenceWBPaper00035610
Curator_confirmedWBPerson2021
Phenotype_assayTreatmentDAPI stainingPaper_evidenceWBPaper00035610
Curator_confirmedWBPerson2021
WBPhenotype:0001040Paper_evidenceWBPaper00000316
Curator_confirmedWBPerson712
WBPhenotype:0001690Paper_evidenceWBPaper00002589
Curator_confirmedWBPerson712
RemarkAnimals were positive for mAb M37 at the L1 stage but not at any other stage, similar to N2 animals.Paper_evidenceWBPaper00002589
Curator_confirmedWBPerson712
PenetranceLowPaper_evidenceWBPaper00002589
Curator_confirmedWBPerson712
Phenotype_assayTemperature27.5Paper_evidenceWBPaper00002589
Curator_confirmedWBPerson712
WBPhenotype:0001999Paper_evidenceWBPaper00037970
Curator_confirmedWBPerson2987
RemarkThe integration of signals for attraction to diacetyl (100x dilute) and avoidance from copper (100 millimolar) was normal (like wild type) in daf-3(e1376) mutants, resulting in the same number of animals crossing the copper barrier to get to the diacetyl spot compared to wild type controls (Figure 5)Paper_evidenceWBPaper00037970
Curator_confirmedWBPerson2987
Affected_byMoleculeWBMol:00002819Paper_evidenceWBPaper00037970
Curator_confirmedWBPerson2987
WBMol:00002862Paper_evidenceWBPaper00037970
Curator_confirmedWBPerson2987
WBPhenotype:0002535Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
RemarkFITC uptake is normal.Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
Reference (17)
MethodDeletion_allele