WormBase Tree Display for Strain: WBStrain00023585
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| WBStrain00023585 | Status | Live | ||
|---|---|---|---|---|
| Genotype | par-2(it315[mCherry::par-2]) III. | |||
| Public_name | KK1254 | |||
| Contains | Gene | WBGene00003917 | ||
| Variation | WBVar02153781 | |||
| Properties | Outcrossed | x0 | ||
| Mutagen | CRISPR_Cas9 | |||
| CGC_received | 06 Jul 2016 00:00:00 | |||
| Location | CGC | |||
| Made_by | WBPerson314 | |||
| Remark | par-2(it315) exhibits a weak maternal effect sterility, suggesting that the tag reduces the protein activity. Note, however, that double homozygous mutants of it315 with pkc-3(it309) or par-6(it310) exhibited partially penetrant and variable maternal effect lethality and maternal effect sterility that was stronger than it315 alone. Thus, although the GFP tags on pkc-3 and par-6 show no effect in an otherwise wild-type background, they do seem to somewhat compromise the activity of the proteins they tag. Made in N2 background. | Inferred_automatically | From CGC strain data | |
| Species | Caenorhabditis elegans |
