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WormBase Tree Display for RNAi: WBRNAi00108767

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Name Class

WBRNAi00108767HomolHomol_homolY38A10A:RNAi
Sequence_infoPCR_productsjj_Y38A10A.5
ExperimentGenotypezcIs4 [Phsp-4::GFP]
Delivered_byBacterial_feeding
InhibitsPredicted_geneY38A10A.5Inferred_automaticallyRNAi_primary
GeneWBGene00000802Inferred_automaticallyRNAi_primary
TranscriptY38A10A.5.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000536747
ReferenceWBPaper00041065
PhenotypeWBPhenotype:0001236Remark"We assessed the effect of knockdown of these 10 genes on ER homeostasis by RNAi treatment in a zcIs4 transgenic strain harboring the hsp-4 promoter-driven GFP transgene that exhibits ER stress-dependent induction of GFP fluorescence. RNAi-mediated knockdown of five genes (crt-1, arf-6, 4R79.2, F48E8.6, and exos-3) elevated GFP expression in intestinal cells (Table 1 and Fig. S1)."
Remark(Table 1) crt-1 RNAi
MethodRNAi