WormBase Tree Display for RNAi: WBRNAi00107847
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WBRNAi00107847 | Homol | Homol_homol | B0336:RNAi | |||
---|---|---|---|---|---|---|
Sequence_info | PCR_product | sjj_B0336.8 | ||||
Experiment | Genotype | gld-1(q485) | ||||
Delivered_by | Bacterial_feeding | |||||
Inhibits | Predicted_gene | B0336.8 | Inferred_automatically | RNAi_primary | ||
Gene | WBGene00002982 | Inferred_automatically | RNAi_primary | |||
Transcript | B0336.8.1 | Inferred_automatically | RNAi_primary | |||
Species | Caenorhabditis elegans | |||||
Reference | WBPaper00049105 | |||||
Phenotype | WBPhenotype:0002397 | Remark | "(tumor cell) Invasion of the vulva region often results in the appearance of a tumor prolapse that protrudes from the vulva (Fig S2C; Movies S2 and S3). Prolapses form by a flow of individual tumor cells and animals with tumor prolapses are motile and often shed their prolapse. In line with modulation of autophagy affecting tumor growth, inhibition of autophagy leads to an increase in the percentage of animals displaying a tumor prolapse both in gld-1 RNAi and mutant animals (Fig S2D and E)." | |||
EQ_annotations | Anatomy_term | WBbt:0006796 | PATO:0000460 | |||
Remark | (Figure S2E) lgg-3 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. | |||||
Method | RNAi |