Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for RNAi: WBRNAi00107847

expand all nodes | collapse all nodes | view schema

Name Class

WBRNAi00107847HomolHomol_homolB0336:RNAi
Sequence_infoPCR_productsjj_B0336.8
ExperimentGenotypegld-1(q485)
Delivered_byBacterial_feeding
InhibitsPredicted_geneB0336.8Inferred_automaticallyRNAi_primary
GeneWBGene00002982Inferred_automaticallyRNAi_primary
TranscriptB0336.8.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00049105
PhenotypeWBPhenotype:0002397Remark"(tumor cell) Invasion of the vulva region often results in the appearance of a tumor prolapse that protrudes from the vulva (Fig S2C; Movies S2 and S3). Prolapses form by a flow of individual tumor cells and animals with tumor prolapses are motile and often shed their prolapse. In line with modulation of autophagy affecting tumor growth, inhibition of autophagy leads to an increase in the percentage of animals displaying a tumor prolapse both in gld-1 RNAi and mutant animals (Fig S2D and E)."
EQ_annotationsAnatomy_termWBbt:0006796PATO:0000460
Remark(Figure S2E) lgg-3 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
MethodRNAi