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WormBase Tree Display for RNAi: WBRNAi00098139

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Name Class

WBRNAi00098139HomolHomol_homolCHROMOSOME_I:RNAi
Sequence_infoPCR_productsjj_F46A9.5
ExperimentLaboratoryWD
Date01 Feb 2008 00:00:00
Genotypecep-1(gk138)
TreatmentLarval stage 2 (L2) hermaphrodites were placed on RNAi plates and allowed to develop until the young adult stage. Animals were exposed to the DNA-alkylating agent N-ethyl-N-nitrosourea (ENU).
Delivered_byBacterial_feeding
InhibitsPredicted_geneF46A9.5Inferred_automaticallyRNAi_primary
GeneWBGene00004807Inferred_automaticallyRNAi_primary
TranscriptF46A9.5.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00031605
Phenotype_not_observedWBPhenotype:0000183RemarkThe cep-1(gk138) mutation completely suppressed the skr-1(RNAi)-induced increase in germ cell apoptosis and accumulation of germ cell corpses in response to the DNA-alkylating agent N-ethyl-N-nitrosourea (ENU).
Affected_byMoleculeWBMol:00003621
WBPhenotype:0001180RemarkThe cep-1(gk138) mutation completely suppressed the skr-1(RNAi)-induced increase in germ cell apoptosis and accumulation of germ cell corpses in response to the DNA-alkylating agent N-ethyl-N-nitrosourea (ENU).
Affected_byMoleculeWBMol:00003621
WBPhenotype:0001918RemarkThe cep-1(gk138) mutation completely suppressed the skr-1(RNAi)-induced increase in germ cell apoptosis and accumulation of germ cell corpses in response to the DNA-alkylating agent N-ethyl-N-nitrosourea (ENU).
Affected_byMoleculeWBMol:00003621
Remark(Figure 2d) skr-1 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
MethodRNAi